Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | GOT1 | P17174 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 5/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.42 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4124108 | 0.85 | MTOR (0.61) | MEN1KMT2ACNR1GOT1MTOR | |
| SCHEMBL4108313 | 0.80 | CNR1 (0.56) | MEN1KMT2ACNR1GOT1MTOR | |
| SCHEMBL4117599 | 0.79 | CNR1 (0.67) | MEN1KMT2ACNR1MTORMCHR1 | |
| SCHEMBL4114216 | 0.79 | MEN1 (0.55) | MEN1KMT2ACNR1MTORMCHR1 | |
| SCHEMBL4113873 | 0.79 | CNR1 (0.67) | MEN1KMT2ACNR1MTORMCHR1 | |
| SCHEMBL4107298 | 0.79 | MEN1 (0.55) | MEN1KMT2ACNR1GOT1MTOR | |
| SCHEMBL4112186 | 0.78 | MEN1 (0.60) | MEN1KMT2ACNR1GOT1MTOR | |
| SCHEMBL4119609 | 0.77 | MEN1 (0.53) | MEN1KMT2ACNR1GOT1MTOR | |
| SCHEMBL4115328 | 0.77 | MCHR1 (0.61) | MEN1KMT2ACNR1GOT1MTOR | |
| SCHEMBL4106222 | 0.77 | MEN1 (0.52) | MEN1KMT2ACNR1GOT1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118330-A1 | Diurea derivatives | ACTIVE BIOTECH AB (SE) | 2009-05-07 | — | — | US | disclosed |
| EP-1711175-A1 | DIUREA DERIVATIVES | Active Biotech AB (SE) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005074919-A1 | DIUREA DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118330-A1 | Diurea derivatives | IL2, CASP2, MAVS | MEN1 4167/4885KMT2A 2720/4885CNR1 3201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.