Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 7/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4112588 | 0.90 | ACHE (0.38) | ACHEBCHE | |
| SCHEMBL4119841 | 0.87 | ACHE (0.38) | ACHECHEK1BCHE | |
| SCHEMBL4120432 | 0.86 | ACHE (0.53) | ACHEBCHE | |
| SCHEMBL4121451 | 0.86 | HTR6 (0.45) | ACHEBCHE | |
| Dimethylamine SCHEMBL4115122 | 0.85 | CHEK1 (0.36) | ACHECHEK1CHEK2ALOX5APFEN1 | |
| Hydrochloric Acid SCHEMBL4112974 | 0.85 | ACHE (0.52) | ACHEBCHE | |
| SCHEMBL4114643 | 0.85 | SLC6A4 (0.41) | ACHEBCHE | |
| SCHEMBL13966088 | 0.85 | ACHE (0.36) | ACHEBCHE | |
| SCHEMBL4121186 | 0.85 | ACHE (0.44) | ACHEBCHE | |
| SCHEMBL4132948 | 0.85 | PDE3B (0.40) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2017275-A1 | BENZISOXAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | ACHE 3716/4885CHEK1 4518/4885CHEK2 4660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.