Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4122102 | 0.87 | AKR1C2 (0.35) | MCL1AKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL4121477 | 0.81 | AKR1C2 (0.40) | BCL2MCL1AKR1C2AKR1C1FFAR1 | |
| SCHEMBL4122535 | 0.81 | MELK (0.35) | MELK | |
| SCHEMBL4113720 | 0.78 | CNR1 (0.35) | MELK | |
| SCHEMBL4620778 | 0.74 | — | — | |
| SCHEMBL421965 | 0.74 | AKR1C4 (0.60) | MCL1AKR1C2AKR1C1FFAR1AKR1C4 | |
| SCHEMBL4120602 | 0.74 | FFAR1 (0.42) | BCL2MCL1AKR1C2AKR1C1FFAR1 | |
| SCHEMBL15141254 | 0.73 | DPP4 (0.36) | — | |
| SCHEMBL15145241 | 0.73 | ALDH1A1 (0.38) | — | |
| SCHEMBL13696932 | 0.73 | AKR1C2 (0.42) | BCL2MCL1AKR1C2AKR1C1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221596-A1 | Substtituted aryl oximes | BAYER CROPSCIENCE AG (DE) | 2009-09-03 | — | — | US | disclosed |
| EP-1883622-A1 | SUBSTITUTED ARYL OXIMES | Bayer CropScience Aktiengesellschaft (DE) | 2008-02-06 | — | — | EP | disclosed |
| WO-2007090434-A1 | SUBSTITUTED ARYL OXIMES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221596-A1 | Substtituted aryl oximes | CYP1A1, PRDX1, CYP1A2 | BCL2 530/4885MCL1 2911/4885AKR1C2 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.