SCHEMBL4115382

SCHEMBL4115382

[CH2]C(C)(C)COC(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4105856 0.84 ALDH1A1 (0.43)
SCHEMBL10361272 0.84
SCHEMBL6249922 0.78 TSHR (0.48)
SCHEMBL4105273 0.78 ALDH1A1 (0.39)
SCHEMBL3199088 0.78 ALDH1A1 (0.48)
SCHEMBL14627793 0.78 ALDH1A1 (0.48)
SCHEMBL697625 0.78
SCHEMBL3847233 0.77 PRKCA (0.41)
SCHEMBL9788741 0.77 MGAM (0.46)
SCHEMBL9293851 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2895517-B1 TWO-COMPONENT POLYURETHANE COMPOSITION SIKA TECH AG (CH) 2020-12-16 EP claimed
CN-104640894-B two-component polyurethane composition SIKA技术股份公司 2018-11-13 CN claimed
US-20150259465-A1 TWO-COMPONENT POLYURETHANE COMPOSITION SIKA TECHNOLOGY AG (CH) 2015-09-17 US claimed
EP-2895517-A1 TWO-COMPONENT POLYURETHANE COMPOSITION Sika Technology AG (CH) 2015-07-22 EP claimed
CN-104640894-A Two-component polyurethane composition SIKA TECHNOLOGY AG 2015-05-20 CN claimed
WO-2014040922-A1 TWO-COMPONENT POLYURETHANE COMPOSITION SIKA TECHNOLOGY AG (CH) 2014-03-20 WO claimed
EP-2706073-A1 Two-component polyurethane composition Sika Technology AG (CH) 2014-03-12 EP claimed
US-20140066429-A1 DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) FOR USE IN TREATMENT OF DISEASES ASSOCIATED WITH A PTEN DEFICIENCY BIOMARIN PHARMACEUTICAL INC. (US) 2014-03-06 US claimed
EP-1097928-B1 5-(2,3-Dialkoxyphenyl)-4,1-benzoxazepin-2-ones as anti-hyperlipidemics TAKEDA PHARMACEUTICAL (JP) 2008-07-16 EP claimed
US-20080153801-A1 Benzoxazepine compounds, their production and use TAKEDA PHARMACEUTICAL COMPANY LIMITED 2008-06-26 US claimed
US-20040072819-A1 Benzoxazepine compounds, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. 2004-04-15 US claimed
US-6613761-B1 (3R,5S)-N- methanesulfonyl-7-chloro-5-(2,3-dimethoxyphenyl) -1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-1,2,3,5-tetrahydro-4, 1-benzoxazepine-3-acetamide, used as antilipemic agents and enzyme inhibitors TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-09-02 US claimed
US-20030078251-A1 Benzoxazepinones and their use as squalene synthase inhibitors TAKEDA CHEMICAL INDUSTRIES LTD. (JP) 2003-04-24 US claimed
EP-1097928-A1 5-(2,3-Dialkoxyphenyl)-4,1-benzoxazepin-2-ones as anti-hyperlipidemics Takeda Chemical Industries, Ltd. (JP) 2001-05-09 EP claimed
EP-0862562-A1 BENZOXAZEPINE COMPOUNDS, THEIR PRODUCTION AND USE AS LIPID LOWERING AGENTS Takeda Chemical Industries, Ltd. (JP) 1998-09-09 EP claimed
WO-1997010224-A1 BENZOXAZEPINE COMPOUNDS, THEIR PRODUCTION AND USE AS LIPID LOWERING AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-03-20 WO claimed
US-20220135901-A1 USE OF (3-ACETOXY-2,2-DIMETHYL-PROPYL) ACETATE IN COMBINATION WITH (3-HYDROXY-2,2-DIMETHYL-PROPYL) ACETATE AS AN AROMA CHEMICAL BASF SE (DE) 2022-05-05 US disclosed
EP-3930669-A1 USE OF (3-ACETOXY-2,2-DIMETHYL-PROPYL) ACETATE IN COMBINATION WITH (3-HYDROXY-2,2-DIMETHYL-PROPYL) ACETATE AS AN AROMA CHEMICAL BASF SE (DE) 2022-01-05 EP disclosed
WO-1997010224-A1 BENZOXAZEPINE COMPOUNDS, THEIR PRODUCTION AND USE AS LIPID LOWERING AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-03-20 WO disclosed
EP-0380316-A2 Preparation of alpha-methylareneacetic acids SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1990-08-01 EP disclosed