⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13459256 | 0.77 | — | — | |
| SCHEMBL3505953 | 0.76 | — | — | |
| SCHEMBL28416707 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL5400276 | 0.76 | NOS1 (0.48) | — | |
| SCHEMBL22924388 | 0.74 | — | — | |
| Iodide SCHEMBL28087743 | 0.74 | LMNA (0.31) | — | |
| SCHEMBL5875630 | 0.70 | IKBKB (0.32) | — | |
| SCHEMBL361464 | 0.67 | — | — | |
| SCHEMBL5155088 | 0.67 | — | — | |
| SCHEMBL10668923 | 0.67 | NOS1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006504796-A | — | — | 2006-02-09 | — | — | JP | claimed |
| EP-1551815-A1 | THIAZOLE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Pfizer Products Inc. (US) | 2005-07-13 | — | — | EP | claimed |
| US-20040152747-A1 | Thiazole compounds for treatment of neurodegenerative disorders | PFIZER INC | 2004-08-05 | — | — | US | claimed |
| WO-2004033439-A1 | THIAZOLE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER PRODUCTS INC. (US) | 2004-04-22 | — | — | WO | claimed |
| EP-2766359-B9 | HETEROCYCLIC COMPOUNDS AND USE THEREOF AS MODULATORS OF TYPE III RECEPTOR TYROSINE KINASES | AMBIT BIOSCIENCES CORP (US) | 2017-04-05 | — | — | EP | disclosed |
| US-20090142553-A1 | Yellow Dye and a Process for Ink Jet Printing Using the Dye | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2009-06-04 | — | — | US | disclosed |
| WO-2007042767-A2 | A YELLOW DYE AND A PROCESS FOR INK JET PRINTING USING THE DYE | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2007-04-19 | — | — | WO | disclosed |
| EP-1551815-A1 | THIAZOLE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Pfizer Products Inc. (US) | 2005-07-13 | — | — | EP | disclosed |
| US-20040152747-A1 | Thiazole compounds for treatment of neurodegenerative disorders | PFIZER INC | 2004-08-05 | — | — | US | disclosed |
| WO-2004033439-A1 | THIAZOLE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER PRODUCTS INC. (US) | 2004-04-22 | — | — | WO | disclosed |