Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 7/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | RAB9A | P51151 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | STAT1 | P42224 | 1/20 | 0.62 |
| ▸ | RAF1 | P04049 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | CDK8 | P49336 | 1/20 | 0.59 |
| ▸ | MITF | O75030 | 2/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113295 | 0.87 | RAB9A (0.71) | TSHRTP53NPC1MAPTSMN1; SMN2 | |
| SCHEMBL196100 | 0.86 | NPC1 (0.75) | TP53NPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL4112924 | 0.85 | SAE1 (0.62) | TSHRTP53NPC1MAPTSMN1; SMN2 | |
| SCHEMBL4104949 | 0.84 | PPARA (0.68) | NPC1MAPTSMN1; SMN2RAB9AMITF | |
| SCHEMBL4123129 | 0.84 | KDR (0.59) | TSHRTP53NPC1MAPTSMN1; SMN2 | |
| SCHEMBL4105865 | 0.84 | RAB9A (0.67) | TSHRTP53NPC1MAPTSMN1; SMN2 | |
| SCHEMBL4118335 | 0.84 | MAPT (0.67) | TSHRTP53NPC1MAPTSMN1; SMN2 | |
| SCHEMBL4106089 | 0.84 | MEN1 (0.60) | TSHRTP53NPC1MAPTSMN1; SMN2 | |
| SCHEMBL4121436 | 0.84 | TSHR (0.78) | TSHRTP53NPC1MAPTSMN1; SMN2 | |
| SCHEMBL4893387 | 0.83 | TP53 (0.87) | TSHRTP53NPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | CNR1, CNR2, OPRL1 | TSHR 536/4885TP53 4802/4885NPC1 927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.