SCHEMBL4116100

SCHEMBL4116100

CCOC(=O)C(=NO)c1ccccc1-c1ccccc1NC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.46
GAA P10253 3/20 0.43
DHODH Q02127 1/20 0.43
MAPT P10636 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LMNA P02545 1/20 0.42
MDM2 Q00987 1/20 0.42
KDM4E B2RXH2 5/20 0.41
POLB P06746 1/20 0.41
ATM Q13315 1/20 0.41
TSHR P16473 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP3A4 P08684 2/20 0.40
USP2 O75604 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
ALOX15 P16050 1/20 0.40
CYP2C19 P33261 1/20 0.40
MAPK10 P53779 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4116097 1.00 L3MBTL1 (0.46) L3MBTL1GAADHODHMAPTSMN1; SMN2
SCHEMBL4115710 0.87 KDM4E (0.42) L3MBTL1GAADHODHMAPTSMN1; SMN2
SCHEMBL4115712 0.87 KDM4E (0.42) L3MBTL1GAADHODHMAPTSMN1; SMN2
SCHEMBL4111199 0.83 L3MBTL1 (0.41) L3MBTL1GAADHODHMAPTSMN1; SMN2
SCHEMBL4111201 0.83 L3MBTL1 (0.41) L3MBTL1GAADHODHMAPTSMN1; SMN2
SCHEMBL4123387 0.82 L3MBTL1 (0.43) L3MBTL1GAADHODHMAPTSMN1; SMN2
SCHEMBL6158724 0.75 TSHR (0.47) L3MBTL1GAADHODHMAPTSMN1; SMN2
SCHEMBL6158733 0.75 TSHR (0.47) L3MBTL1GAADHODHMAPTSMN1; SMN2
SCHEMBL10441874 0.75 KDM4E (0.49) L3MBTL1GAAMAPTSMN1; SMN2LMNA
SCHEMBL4110223 0.74 SMN1; SMN2 (0.42) L3MBTL1GAADHODHMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8258302-B2 Method for producing benzazepinone API CORPORATION (JP) 2012-09-04 US disclosed
US-20090171090-A1 METHOD FOR PRODUCING BENZAZEPINONE API CORPORATION (JP) 2009-07-02 US disclosed
EP-1985615-A1 METHOD FOR PRODUCING BENZAZEPINONE API Corporation (JP) 2008-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090171090-A1 METHOD FOR PRODUCING BENZAZEPINONE NISCH, GABBR1, GABBR2 L3MBTL1 4853/4885GAA 682/4885DHODH 519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.