SCHEMBL4117115

SCHEMBL4117115

c1ccc([PH](Cc2ccccc2C[PH](c2ccccc2)(c2ccccc2)c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
DPP4 P27487 1/20 0.31
AKR1B1 P15121 1/20 0.31
HSPA5 P11021 1/20 0.31
CALM1 P0DP23 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16368768 0.89 TRPA1 (0.37) TSHR
SCHEMBL19526126 0.89 GABRA1 (0.38)
SCHEMBL8652770 0.84 MAPT (0.31)
SCHEMBL5972854 0.84 TAAR1 (0.45)
SCHEMBL14520594 0.84 IDO1 (0.46) TSHR
SCHEMBL5973110 0.84 TAAR1 (0.43) TSHR
SCHEMBL17004397 0.84 TAAR1 (0.43) TSHR
SCHEMBL4547674 0.84 HSPA5 (0.50) TSHRAKR1B1HSPA5
SCHEMBL28694881 0.84 TAAR1 (0.43)
Hydrochloric Acid SCHEMBL29202383 0.82 TAAR1 (0.42) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420295-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2013-04-16 US disclosed
EP-2112555-A2 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2009-10-28 EP disclosed
US-20090246690-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed