Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156987 | 0.85 | TSHR (0.43) | TSHRTDP1 | |
| SCHEMBL11461590 | 0.76 | TSHR (0.35) | TSHRTDP1 | |
| SCHEMBL22007399 | 0.73 | ALDH1A1 (0.39) | — | |
| SCHEMBL19245901 | 0.73 | TSHR (0.33) | TSHRTDP1 | |
| SCHEMBL20952956 | 0.73 | TSHR (0.33) | TSHRTDP1 | |
| SCHEMBL19415093 | 0.73 | TSHR (0.33) | TSHRTDP1 | |
| SCHEMBL12285415 | 0.71 | TSHR (0.38) | TSHRTDP1 | |
| SCHEMBL16872763 | 0.71 | — | — | |
| SCHEMBL18612961 | 0.71 | TSHR (0.38) | TSHRTDP1 | |
| SCHEMBL22664282 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4296029-A | Process for preparing hexahydroazepine, piperidine and pyrrolidine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1981-10-20 | — | — | US | claimed |
| EP-3724699-B1 | METHOD FOR PRODUCING MPS-COMPATIBLE WATER GRADIENT CONTACT LENSES | ALCON INC (CH) | 2023-07-26 | — | — | EP | disclosed |
| US-20230142274-A1 | SUBSTITUTED ARYL COMPOUND | NANJING ZAIMING PHARMACEUTICAL CO., LTD. (CN) | 2023-05-11 | — | — | US | disclosed |
| CN-108291171-B | Synergistic lubricating oil composition containing mixture of olefin copolymer dispersant type viscosity improver and amine compound | 雪佛龙奥伦耐有限责任公司 | 2022-02-01 | — | — | CN | disclosed |
| US-20210340111-A1 | COMPOSITION OF SCALABLE THYROINTEGRIN ANTAGONISTS WITH IMPROVED RETENTION IN TUMORS | NANOPHARMACEUTICALS LLC | 2021-11-04 | — | — | US | disclosed |
| US-20210253613-A1 | PHOSPHORUS IMIDAZOQUINOLINE AMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS THEREOF | CANWELL BIOTECH LTD (CN) | 2021-08-19 | — | — | US | disclosed |
| EP-2885384-B1 | LUBRICANT COMPOSITION COMPRISING ACYCLIC HINDERED AMINES | BASF SE (DE) | 2021-05-05 | — | — | EP | disclosed |
| EP-2760958-B1 | SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES | EQUISTAR CHEM LP (US) | 2020-08-12 | — | — | EP | disclosed |
| US-10662391-B2 | Lubricating oil compositions containing borated dispersants and amine compounds and methods of making and using same | CHEVRON ORONITE COMPANY LLC (US) | 2020-05-26 | — | — | US | disclosed |
| CN-110790725-A | Preparation method of lubricating oil additive containing thiadiazole group | 太平洋联合(北京)石油化工有限公司 | 2020-02-14 | — | — | CN | disclosed |
| EP-0021772-B1 | METHOD OF PREPARING 2-OXO- AND 2-UNSUBSTITUTED-HEXAHYDROAZEPINE DERIVATIVES | JOHN WYETH & BROTHER LIMITED (GB) | 1985-01-02 | — | — | EP | disclosed |
| EP-0054384-B1 | PROCESS FOR PREPARING PYRIDINE DERIVATIVES | JOHN WYETH & BROTHER LIMITED (GB) | 1984-06-27 | — | — | EP | disclosed |
| EP-0021552-B1 | HEXAHYDROAZEPINE, PIPERIDINE AND PYRROLIDINE DERIVATIVES AND PROCESSES FOR PREPARING THEM | JOHN WYETH & BROTHER LIMITED (GB) | 1983-01-26 | — | — | EP | disclosed |
| EP-0054384-A1 | Process for preparing pyridine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1982-06-23 | — | — | EP | disclosed |
| US-4296029-A | Process for preparing hexahydroazepine, piperidine and pyrrolidine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1981-10-20 | — | — | US | disclosed |
| EP-0021772-A1 | Method of preparing 2-oxo- and 2-unsubstituted-hexahydroazepine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1981-01-07 | — | — | EP | disclosed |
| EP-0021552-A1 | Hexahydroazepine, piperidine and pyrrolidine derivatives and processes for preparing them | JOHN WYETH & BROTHER LIMITED (GB) | 1981-01-07 | — | — | EP | disclosed |
| US-4197241-A | Hexahydroazepine, piperidine and pyrrolidine derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1980-04-08 | — | — | US | disclosed |
| EP-0003253-A1 | Hexahydroazepine, piperidine and pyrrolidine derivatives and processes for making and using them | JOHN WYETH & BROTHER LIMITED (GB) | 1979-08-08 | — | — | EP | disclosed |
| US-4006190-A | Production of hydroxyl compounds | CELANESE CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253613-A1 | PHOSPHORUS IMIDAZOQUINOLINE AMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS THEREOF | TLR8, TLR7, TLR9 | TSHR 2135/4885TDP1 976/4885 |
| US-20210340111-A1 | COMPOSITION OF SCALABLE THYROINTEGRIN ANTAGONISTS WITH IMPROVED RETENTION IN TUMORS | EGFR, TEK, HDGF | TSHR 11/4885TDP1 3511/4885 |
| US-20230142274-A1 | SUBSTITUTED ARYL COMPOUND | RAD51, FANCI, BLM | TSHR 3887/4885TDP1 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.