Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.45 |
| ▸ | GHSR | Q92847 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4134263 | 0.87 | NAALAD2 (0.47) | NAALAD2GHSRMAPTALOX15KMT2A | |
| SCHEMBL13775774 | 0.74 | — | — | |
| SCHEMBL28504133 | 0.68 | NAALAD2 (0.60) | NAALAD2GHSR | |
| SCHEMBL21515089 | 0.68 | NAALAD2 (0.60) | NAALAD2GHSR | |
| SCHEMBL22069732 | 0.68 | NAALAD2 (0.51) | NAALAD2GHSRALDH1A1 | |
| Hydrochloric Acid SCHEMBL21494731 | 0.67 | NAALAD2 (0.58) | NAALAD2GHSR | |
| SCHEMBL7341365 | 0.67 | NAALAD2 (0.50) | NAALAD2GHSRMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL28501489 | 0.67 | NAALAD2 (0.58) | NAALAD2GHSR | |
| SCHEMBL15254266 | 0.67 | NAALAD2 (0.49) | NAALAD2GHSRMAPTALOX15KMT2A | |
| SCHEMBL15254268 | 0.66 | NAALAD2 (0.57) | NAALAD2GHSRMAPTALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181942-A1 | TRICYCLIC COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1939205-A1 | TRICYCLIC COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181942-A1 | TRICYCLIC COMPOUNDS | FDFT1, COASY, HMGCR | NAALAD2 1319/4885GHSR 796/4885MAPT 4428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.