SCHEMBL4119197

SCHEMBL4119197

COc1cc(C)c(S(=O)(=O)N(C)CCOCC(=O)N2CC[C](c3ccncc3)CC2)c(C)c1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB1 P46663 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3813821 0.87 BDKRB1 (0.64) BDKRB1
SCHEMBL3407151 0.87 BDKRB1 (0.64) BDKRB1
SCHEMBL3410734 0.85 BDKRB1 (0.63) BDKRB1
SCHEMBL3816585 0.85 BDKRB1 (0.62) BDKRB1
Hydrochloric Acid SCHEMBL3412258 0.85 BDKRB1 (0.62) BDKRB1
SCHEMBL13970729 0.85 BDKRB1 (0.77) BDKRB1
SCHEMBL4091231 0.84 BDKRB1 (0.59) BDKRB1
SCHEMBL3454607 0.84 BDKRB1 (0.55) BDKRB1
SCHEMBL3408566 0.84 BDKRB1 (0.61) BDKRB1
SCHEMBL4472442 0.84 BDKRB1 (0.79) BDKRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090253669-A1 Substituted Sulfonamide Compounds GRUENENTHAL GMBH (DE) 2009-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090253669-A1 Substituted Sulfonamide Compounds SULT2A1, STS, SULT1A1 BDKRB1 3589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.