SCHEMBL4119592

SCHEMBL4119592

C[Ge](C)(C)C(=O)c1ccc(OCCCCCCOc2ccc(C(=O)[Ge](C)(C)C)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.67
▸ L3MBTL1 Q9Y468 1/20 0.63
▸ TP53 P04637 1/20 0.59
▸ TSHR P16473 1/20 0.59
▸ PLA2G4B P0C869 4/20 0.57
▸ RARB P10826 3/20 0.54
▸ HTT P42858 1/20 0.54
▸ PRMT1 Q99873 3/20 0.52
▸ F2 P00734 2/20 0.52
▸ ST14 Q9Y5Y6 2/20 0.52
▸ PLAU P00749 1/20 0.52
▸ MAPT P10636 1/20 0.52
▸ PRMT5 O14744 1/20 0.52
▸ SLC22A2 O15244 1/20 0.52
▸ SLC22A1 O15245 1/20 0.52
▸ TMPRSS2 O15393 1/20 0.52
▸ PTP4A3 O75365 1/20 0.52
▸ SLC22A3 O75751 1/20 0.52
▸ F10 P00742 1/20 0.52
▸ PLG P00747 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4127412 0.79 TP53 (0.56) GAAL3MBTL1TP53TSHRPLA2G4B
SCHEMBL2180731 0.78 TP53 (0.82) GAAL3MBTL1TP53TSHRPLA2G4B
SCHEMBL2183388 0.78 TP53 (0.82) GAAL3MBTL1TP53TSHRPLA2G4B
SCHEMBL26136333 0.78 TP53 (0.82) GAAL3MBTL1TP53TSHRPLA2G4B
SCHEMBL2181009 0.78 TP53 (0.82) GAAL3MBTL1TP53TSHRPLA2G4B
SCHEMBL209561 0.78 TP53 (0.82) GAAL3MBTL1TP53TSHRPLA2G4B
SCHEMBL14097198 0.78 TP53 (0.82) GAAL3MBTL1TP53TSHRPLA2G4B
SCHEMBL18868405 0.78 L3MBTL1 (1.00) GAAL3MBTL1TP53TSHRPLA2G4B
SCHEMBL7911508 0.78 TP53 (0.82) GAAL3MBTL1TP53TSHRPLA2G4B
SCHEMBL20278587 0.77 GAA (0.67) GAAL3MBTL1TP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113292594-B Long wave absorption photoinitiator 义获嘉伟瓦登特公司 2023-09-05 — — CN disclosed
US-11401287-B2 Long-wave absorbing photoinitiators IVOCLAR VIVADENT AG (LI) 2022-08-02 — — US disclosed
CN-113292594-A Long-wave light-absorbing initiator 义获嘉伟瓦登特公司 2021-08-24 — — CN disclosed
US-8829067-B2 Polymerizable compositions with initiators containing several Ge atoms IVOCLAR VIVADENT AG (LI) 2014-09-09 — — US disclosed
US-20090239967-A1 POLYMERIZABLE COMPOSITIONS WITH INITIATORS CONTAINING SEVERAL GE ATOMS IVOCLAR VIVADENT AG (LI) 2009-09-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11401287-B2 Long-wave absorbing photoinitiators CBR3, STRA6, NR2E3 GAA 4538/4885L3MBTL1 1513/4885TP53 2921/4885
US-20090239967-A1 POLYMERIZABLE COMPOSITIONS WITH INITIATORS CONTAINING SEVERAL GE ATOMS GRIA1, COG1, GRIA4 GAA 316/4885L3MBTL1 3186/4885TP53 4349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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