Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1567185 | 1.00 | APP (0.41) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL1567658 | 1.00 | APP (0.41) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL1031382 | 1.00 | APP (0.41) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL1567257 | 1.00 | APP (0.41) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL1028935 | 0.98 | APP (0.43) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL7529214 | 0.96 | APP (0.41) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL1029720 | 0.92 | APP (0.44) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL7534292 | 0.90 | APP (0.43) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL999988 | 0.83 | LMNA (0.40) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL1858134 | 0.82 | LMNA (0.38) | LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1864645-B1 | FLUORINE ION-RELEASABLE COMPOSITION FOR DENTAL PURPOSES | KURARAY NORITAKE DENTAL INC (JP) | 2013-05-22 | — | — | EP | disclosed |
| US-20090068123-A1 | FLUORINE ION-RELEASABLE COMPOSITION FOR DENTAL PURPOSES | KURARAY MEDICAL INC (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20080182919-A1 | Dental Restorative Composition | SUN MEDICAL CO., LTD. (JP) | 2008-07-31 | — | — | US | disclosed |
| EP-1864645-A1 | FLUORINE ION-RELEASABLE COMPOSITION FOR DENTAL PURPOSES | Kuraray Medical Inc. (JP) | 2007-12-12 | — | — | EP | disclosed |
| EP-1854447-A1 | DENTAL RESTORATION MATERIAL COMPOSITION | SUN MEDICAL CO., LTD. (JP) | 2007-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182919-A1 | Dental Restorative Composition | PARG, PARN, FHIT | APP 2532/4885LMNA 682/4885SLC6A6 4370/4885 |
| US-20090068123-A1 | FLUORINE ION-RELEASABLE COMPOSITION FOR DENTAL PURPOSES | ITGA5, ITGAL, PHOSPHO1 | APP 1246/4885LMNA 1908/4885SLC6A6 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.