⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909344 | 0.93 | TSHR (0.52) | — | |
| SCHEMBL7119890 | 0.85 | — | — | |
| SCHEMBL1485881 | 0.77 | TSHR (0.48) | — | |
| SCHEMBL1485879 | 0.77 | TSHR (0.48) | — | |
| SCHEMBL6280915 | 0.77 | TSHR (0.48) | — | |
| SCHEMBL175321 | 0.74 | — | — | |
| SCHEMBL646484 | 0.74 | — | — | |
| SCHEMBL387510 | 0.72 | — | — | |
| SCHEMBL3035311 | 0.72 | ADH1B (0.52) | — | |
| SCHEMBL11142797 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640248-B1 | AMINOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING ADAMADLE BIOTECHNOLOGY LLC (CN) | 2023-08-23 | — | — | EP | claimed |
| US-11352352-B2 | Aminopyrimidine compound, preparation method therefor and use thereof | Beijing Adamadle Biotechnology Limited Liability Company (CN) | 2022-06-07 | — | — | US | claimed |
| EP-3640248-A1 | AMINOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Beijing Adamadle Biotechnology Limited Liability Company (CN) | 2020-04-22 | — | — | EP | claimed |
| US-20200087296-A1 | AMINOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Beijing Adamadle Biotechnology Limited Liability Company (CN) | 2020-03-19 | — | — | US | claimed |
| WO-2019154366-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏奥赛康药业有限公司 | 2019-08-15 | — | — | WO | claimed |
| CN-104797581-A | HETEROARYL ALKYNE COMPOUND AND APPLICATION THEREOF | NANJING SANHOME PHARMACEUTICAL CO LTD | 2015-07-22 | — | — | CN | claimed |
| CN-1832920-A | Aryl and heteroaryl compounds, compositions, and methods of use | TRANSTECH PHARMA INC (US) | 2006-09-13 | — | — | CN | claimed |
| EP-1660439-A2 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Transtech Pharma, Inc. (US) | 2006-05-31 | — | — | EP | claimed |
| US-20050059705-A1 | Aryl and heteroaryl compounds, compositions, and methods of use | VTVX HOLDINGS I LLC | 2005-03-17 | — | — | US | claimed |
| WO-2005014533-A2 | ARYL AND HETEROARYL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | TRANSTECH PHARMA, INC. (US) | 2005-02-17 | — | — | WO | claimed |
| EP-0378767-B1 | Method for the oligomerisation of hexafluoropropene oxide | HOECHST AG (DE) | 1994-08-31 | — | — | EP | claimed |
| EP-0246114-B1 | PHOTOCHROMIC SPIROPYRAN COMPOUNDS | GEC-MARCONI LIMITED (GB) | 1992-09-02 | — | — | EP | claimed |
| US-4973748-A | PERFLUOROCARBONYL FLUORIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-27 | — | — | US | claimed |
| US-4826977-A | Photochromic spiropyran compounds | THE PLESSEY COMPANY PLC (GB) | 1989-05-02 | — | — | US | claimed |
| EP-0246114-A2 | Photochromic spiropyran compounds | GEC-MARCONI LIMITED (GB) | 1987-11-19 | — | — | EP | claimed |
| EP-3640248-B1 | AMINOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING ADAMADLE BIOTECHNOLOGY LLC (CN) | 2023-08-23 | — | — | EP | disclosed |
| US-11352352-B2 | Aminopyrimidine compound, preparation method therefor and use thereof | Beijing Adamadle Biotechnology Limited Liability Company (CN) | 2022-06-07 | — | — | US | disclosed |
| US-4820694-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0262903-A2 | New acyl derivatives of 20-modified tylosin and desmycosin compounds | ELI LILLY AND COMPANY (US) | 1988-04-06 | — | — | EP | disclosed |
| EP-0262905-A2 | Modifications of 3-0-demethyl-mycinose in macrocin and lactenocin | ELI LILLY AND COMPANY (US) | 1988-04-06 | — | — | EP | disclosed |