Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4119803 | 0.93 | — | — | |
| SCHEMBL7119890 | 0.83 | — | — | |
| SCHEMBL15321993 | 0.77 | TSHR (0.52) | TSHRALDH1A1FAAHTRPV1 | |
| SCHEMBL15321994 | 0.77 | TSHR (0.52) | TSHRALDH1A1FAAHTRPV1 | |
| SCHEMBL644844 | 0.75 | — | — | |
| SCHEMBL16892544 | 0.73 | TSHR (0.52) | TSHRFAAHTRPV1EPHX1ADH1B | |
| SCHEMBL10886305 | 0.73 | TSHR (0.52) | TSHRFAAHTRPV1EPHX1ADH1B | |
| SCHEMBL1405793 | 0.73 | ADH1B (0.50) | TSHRALDH1A1FAAHTRPV1EPHX1 | |
| SCHEMBL5646725 | 0.73 | TSHR (0.52) | TSHRFAAHTRPV1EPHX1ADH1B | |
| SCHEMBL22122694 | 0.73 | TSHR (0.52) | TSHRFAAHTRPV1EPHX1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360760-B1 | Pipecolic acid containing cyclopeptolides, their preparation and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1995-02-15 | — | — | EP | claimed |
| EP-0360760-A2 | Pipecolic acid containing cyclopeptolides, their preparation and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1990-03-28 | — | — | EP | claimed |
| US-5643869-A | Pipecolic acid-containing peptolides, their preparation and pharmaceutical compositions containing them | SANDOZ LTD. (CH) | 1997-07-01 | — | — | US | disclosed |
| EP-0360760-B1 | Pipecolic acid containing cyclopeptolides, their preparation and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1995-02-15 | — | — | EP | disclosed |
| EP-0360760-A2 | Pipecolic acid containing cyclopeptolides, their preparation and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1990-03-28 | — | — | EP | disclosed |