⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4127177 | 0.69 | — | — | |
| SCHEMBL7995031 | 0.67 | LMNA (0.35) | — | |
| SCHEMBL2840987 | 0.67 | LMNA (0.35) | — | |
| SCHEMBL942111 | 0.67 | — | — | |
| SCHEMBL13868138 | 0.65 | — | — | |
| SCHEMBL38852 | 0.65 | — | — | |
| SCHEMBL24520774 | 0.64 | — | — | |
| SCHEMBL23484649 | 0.64 | — | — | |
| SCHEMBL72618 | 0.63 | — | — | |
| SCHEMBL107778 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090093468-A1 | Peptide Deformylase Inhibitors | ARPIDA A/S (DK) | 2009-04-09 | — | — | US | disclosed |
| US-20070066672-A1 | Benzimidazole derivatives and use thereof as peptide deformylase inhibitors | ARPIDA A/S (DK) | 2007-03-22 | — | — | US | disclosed |
| EP-1732907-A1 | PEPTIDE DEFORMYLASE INHIBITORS | Arpida A/S (DK) | 2006-12-20 | — | — | EP | disclosed |
| EP-1677785-A1 | BENZIMIDAZOLE DERIVATIVES AND USE THEREOF AS PEPTIDE DEFORMYLASE INHIBITORS | Arpida A/S (DK) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005092872-A1 | PEPTIDE DEFORMYLASE INHIBITORS | ARPIDA A/S (DK) | 2005-10-06 | — | — | WO | disclosed |
| WO-2005037272-A1 | BENZIMIDAZOLE DERIVATIVES AND USE THEREOF AS PEPTIDE DEFORMYLASE INHIBITORS | ARPIDA A/S (DK) | 2005-04-28 | — | — | WO | disclosed |