Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4121763 | 1.00 | ALDH1A1 (0.42) | ALDH1A1DUSP3DUSP22KCNJ1RAB9A | |
| Acetic Acid SCHEMBL4137421 | 0.85 | RXFP1 (0.42) | ALDH1A1KCNJ1RAB9ASMN1; SMN2KDM4E | |
| Acetic Acid SCHEMBL4137417 | 0.85 | RXFP1 (0.42) | ALDH1A1KCNJ1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4123875 | 0.83 | POLB (0.51) | ALDH1A1DUSP3DUSP22RAB9AKDM4E | |
| SCHEMBL4123871 | 0.83 | POLB (0.51) | ALDH1A1DUSP3DUSP22RAB9AKDM4E | |
| SCHEMBL4133860 | 0.82 | DUSP22 (0.49) | ALDH1A1DUSP3DUSP22RAB9ASMN1; SMN2 | |
| SCHEMBL4133862 | 0.82 | DUSP22 (0.49) | ALDH1A1DUSP3DUSP22RAB9ASMN1; SMN2 | |
| SCHEMBL4127839 | 0.81 | PDE4B (0.42) | DUSP3DUSP22GAAHTTPTPN22 | |
| SCHEMBL4127838 | 0.81 | PDE4B (0.42) | DUSP3DUSP22GAAHTTPTPN22 | |
| SCHEMBL4634749 | 0.81 | ALOX5 (0.52) | MEN1KMT2APTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088432-A1 | Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors | TORRENT PHARMACEUTICALS LIMITED (IN) | 2009-04-02 | — | — | US | claimed |
| US-20090088432-A1 | Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors | TORRENT PHARMACEUTICALS LIMITED (IN) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088432-A1 | Thiazolinones and Oxazolinones and their Use as Ptp1b Inhibitors | PTPRF, PTPA, PTPRJ | ALDH1A1 216/4885DUSP3 66/4885DUSP22 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.