SCHEMBL412237

SCHEMBL412237

Fc1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
BCL2L1 Q07817 2/20 0.52
BAD Q92934 1/20 0.52
MAPK1 P28482 1/20 0.50
NFE2L2 Q16236 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MMP3 P08254 1/20 0.50
KIF11 P52732 1/20 0.50
MEN1 O00255 1/20 0.48
POLB P06746 1/20 0.48
KMT2A Q03164 1/20 0.48
ALDH1A3 P47895 1/20 0.48
PTGS1 P23219 3/20 0.48
PTGS2 P35354 2/20 0.45
ALOX5 P09917 1/20 0.45
FLT3 P36888 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7938359 1.00 ALDH1A1 (0.60) ALDH1A1BCL2L1BADMAPK1NFE2L2
SCHEMBL12444110 1.00 ALDH1A1 (0.60) ALDH1A1BCL2L1BADMAPK1NFE2L2
SCHEMBL29130498 0.97 ALDH1A1 (0.56) ALDH1A1BCL2L1BADMAPK1NFE2L2
SCHEMBL11491288 0.97 ALDH1A1 (0.56) ALDH1A1BCL2L1BADMAPK1NFE2L2
Water SCHEMBL3745867 0.97 ALDH1A1 (0.56) ALDH1A1BCL2L1BADMAPK1NFE2L2
Water SCHEMBL6337149 0.97 ALDH1A1 (0.56) ALDH1A1BCL2L1BADMAPK1NFE2L2
SCHEMBL28421428 0.94 ALDH1A1 (0.53) ALDH1A1BCL2L1BADMAPK1NFE2L2
Hydrochloric Acid SCHEMBL28569432 0.94 ALDH1A1 (0.53) ALDH1A1BCL2L1BADMAPK1NFE2L2
SCHEMBL13682555 0.91 ALDH1A1 (0.50) ALDH1A1BCL2L1BADMAPK1NFE2L2
SCHEMBL28348758 0.91 BCL2L1 (0.52) ALDH1A1BCL2L1BADMAPK1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1539 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250154179-A1 GOLD (I) GEFITINIB DERIVATIVES AND PREPARATION METHOD AND APPLICATION THEREOF TONGJI HOSPITAL, TONGJI MEDICAL COLLEGE, HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2025-05-15 US claimed
CN-119976789-A Preparation method of carboxylate cross-linked starch derived hard carbon anode material and application of carboxylate cross-linked starch derived hard carbon anode material in sodium ion battery 南开大学 2025-05-13 CN claimed
US-20250118806-A1 DUAL-ADDITIVE ELECTROLYTE SOLUTIONS FOR OVERCHARGE RESPONSE MITIGATION FORD GLOBAL TECH LLC (US) 2025-04-10 US claimed
US-12206071-B2 Dual-additive electrolyte solutions for overcharge response mitigation FORD GLOBAL TECHNOLOGIES, LLC (US) 2025-01-21 US claimed
US-20240339730-A1 ELECTROCHEMICAL DEVICE NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2024-10-10 US claimed
CN-118724768-A N-alkyl substituted nitrogen-containing compound and preparation method thereof 武汉光化学技术研究院 2024-10-01 CN claimed
EP-4411963-A2 ELECTROCHEMICAL DEVICE Ningde Amperex Technology Ltd. (CN) 2024-08-07 EP claimed
US-12057602-B2 Electrochemical device NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2024-08-06 US claimed
EP-3966880-B1 ELECTROCHEMICAL DEVICE NINGDE AMPEREX TECHNOLOGY LTD (CN) 2024-07-31 EP claimed
CN-118146510-A Heat-resistant polyarylether resin, synthesis method and application thereof in coating aspect 浙江鹏孚隆新材料有限公司 2024-06-07 CN claimed
EP-0643054-A2 Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods FUJIREBIO Inc. (JP) 1995-03-15 EP claimed
US-5393780-A Anticholesterol, antilipemic agents FUJIREBIO INC. (JP) 1995-02-28 US claimed
EP-0616999-A2 4-Fluorobiphenyl derivatives FUJIREBIO Inc. (JP) 1994-09-28 EP claimed
EP-0617000-A2 4-Fluorobiphenyl derivatives FUJIREBIO Inc. (JP) 1994-09-28 EP claimed
EP-0110671-B1 PREPARATION OF OPTICALLY ACTIVE ALPHA-ARYLALKANOIC ACIDS AND PRECURSORS THEREOF SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1986-05-21 EP claimed
US-4473487-A 4-Fluorobiphenyl derivatives, their preparation, and dielectrics and electro-optical display element containing them MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-09-25 US claimed
EP-0110671-A1 Preparation of optically active alpha-arylalkanoic acids and precursors thereof SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1984-06-13 EP claimed
US-4144397-A Preparation of 2-aryl-propionic acids by direct coupling utilizing a mixed magnesium halide complex SYNTEX CORPORATION (US) 1979-03-13 US claimed
US-4016196-A HEATING GLYCIDIC ESTERS NISSHIN FLOUR MILLING CO., LTD. (JA) 1977-04-05 US claimed
US-4007217-A FROM A GLYCIDATE NISSHIN FLOUR MILLING CO., LTD. (JA) 1977-02-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154179-A1 GOLD (I) GEFITINIB DERIVATIVES AND PREPARATION METHOD AND APPLICATION THEREOF EGFR, MAP2K4, MAP2K3 ALDH1A1 1710/4885BCL2L1 1045/4885BAD 1020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.