SCHEMBL7938359

SCHEMBL7938359

Fc1ccc(-c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
BCL2L1 Q07817 2/20 0.52
BAD Q92934 1/20 0.52
MAPK1 P28482 1/20 0.50
NFE2L2 Q16236 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MMP3 P08254 1/20 0.50
KIF11 P52732 1/20 0.50
MEN1 O00255 1/20 0.48
POLB P06746 1/20 0.48
KMT2A Q03164 1/20 0.48
ALDH1A3 P47895 1/20 0.48
PTGS1 P23219 3/20 0.48
PTGS2 P35354 2/20 0.45
ALOX5 P09917 1/20 0.45
FLT3 P36888 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL412237 1.00 ALDH1A1 (0.60) ALDH1A1BCL2L1BADMAPK1NFE2L2
SCHEMBL12444110 1.00 ALDH1A1 (0.60) ALDH1A1BCL2L1BADMAPK1NFE2L2
SCHEMBL29130498 0.97 ALDH1A1 (0.56) ALDH1A1BCL2L1BADMAPK1NFE2L2
SCHEMBL11491288 0.97 ALDH1A1 (0.56) ALDH1A1BCL2L1BADMAPK1NFE2L2
Water SCHEMBL3745867 0.97 ALDH1A1 (0.56) ALDH1A1BCL2L1BADMAPK1NFE2L2
Water SCHEMBL6337149 0.97 ALDH1A1 (0.56) ALDH1A1BCL2L1BADMAPK1NFE2L2
SCHEMBL28421428 0.94 ALDH1A1 (0.53) ALDH1A1BCL2L1BADMAPK1NFE2L2
Hydrochloric Acid SCHEMBL28569432 0.94 ALDH1A1 (0.53) ALDH1A1BCL2L1BADMAPK1NFE2L2
SCHEMBL13682555 0.91 ALDH1A1 (0.50) ALDH1A1BCL2L1BADMAPK1NFE2L2
SCHEMBL28348758 0.91 BCL2L1 (0.52) ALDH1A1BCL2L1BADMAPK1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112300011-B Aryl amine derivative containing bifluorene and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2021-11-09 CN disclosed
CN-112300011-A Aryl amine derivative containing bifluorene and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2021-02-02 CN disclosed
US-20200148538-A1 SURFACE-MODIFIED INORGANIC NITRIDE, COMPOSITION, THERMALLY CONDUCTIVE MATERIAL, AND DEVICE WITH THERMALLY CONDUCTIVE LAYER FUJIFILM CORPORATION (JP) 2020-05-14 US disclosed
US-9957441-B2 Amine-based compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-01 US disclosed
US-9054324-B2 Organic molecular memory KABUSHIKI KAISHA TOSHIBA (JP) 2015-06-09 US disclosed
US-9047941-B2 Organic molecular memory KABUSHIKI KAISHA TOSHIBA (JP) 2015-06-02 US disclosed
WO-2013004333-A1 BIMESOGENIC COMPOUNDS MERCK PATENT GMBH (DE) 2013-01-10 WO disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed