SCHEMBL412244

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10189733	0.87	MAPT (0.47)	MEN1KMT2AGFERMAPTALOX12
	SCHEMBL412221	0.86	TUBB4A (0.43)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL13252806	0.83	PDGFRB (0.41)	MAPTLMNAKDM4ETUBB4ATUBB
	SCHEMBL411698	0.83	TUBB4A (0.56)	MEN1KMT2AMAPTLMNAKDM4E
	SCHEMBL13041102	0.82	PDGFRB (0.41)	MAPTLMNAKDM4ETSHRTUBB4A
	SCHEMBL412499	0.82	PDGFRB (0.41)	MAPTLMNAKDM4ETUBB4ATUBB
	SCHEMBL13041108	0.82	KDR (0.52)	MEN1KMT2AMAPTKDM4EMAPK1
	SCHEMBL411388	0.82	TUBB4A (0.54)	MEN1KMT2AMAPTLMNAKDM4E
	SCHEMBL411535	0.81	MEN1 (0.48)	MEN1KMT2AGFERMAPTALOX12
	SCHEMBL412500	0.81	PDGFRB (0.41)	KDM4ETUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.