Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3796712 | 0.89 | HDAC6 (0.46) | KMT2AMAPTHDAC6POLBPKM | |
| SCHEMBL3663393 | 0.89 | KMT2A (0.56) | KMT2ALMNAKDM4AALDH1A1HTT | |
| SCHEMBL3659738 | 0.85 | POLB (0.56) | KMT2ALMNAPOLBMEN1 | |
| SCHEMBL4113485 | 0.85 | KDM4A (0.52) | KMT2ALMNAKDM4AALDH1A1HTT | |
| SCHEMBL3663347 | 0.84 | KMT2A (0.58) | KMT2ALMNAKDM4AALDH1A1HTT | |
| SCHEMBL3664010 | 0.83 | LMNA (0.55) | KMT2ALMNAKDM4AALDH1A1HTT | |
| SCHEMBL3661725 | 0.83 | LMNA (0.55) | KMT2ALMNAKDM4AALDH1A1HTT | |
| SCHEMBL3716864 | 0.81 | MAPT (0.56) | KMT2AMAPTTSHRPOLBPKM | |
| SCHEMBL2980866 | 0.80 | HDAC1 (0.39) | LMNASMN1; SMN2KCNH2 | |
| SCHEMBL3664165 | 0.79 | KMT2A (0.52) | KMT2ALMNAALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099243-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099243-A1 | ORGANIC COMPOUNDS | SLCO4C1, SLCO1B1, SLCO1B3 | KMT2A 2020/4885LMNA 2430/4885KDM4A 3348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.