⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682316 | 0.82 | — | — | |
| SCHEMBL7241523 | 0.82 | ALDH1A1 (0.72) | — | |
| SCHEMBL77978 | 0.80 | — | — | |
| SCHEMBL2695815 | 0.79 | ALDH1A1 (0.62) | — | |
| SCHEMBL4288375 | 0.79 | ALDH1A1 (0.62) | — | |
| SCHEMBL4288379 | 0.79 | EGLN3 (0.69) | — | |
| SCHEMBL12391736 | 0.79 | ALDH1A1 (0.62) | — | |
| SCHEMBL1179222 | 0.78 | — | — | |
| SCHEMBL85945 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL1904485 | 0.78 | ALDH1A1 (0.96) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200166526-A1 | METHODS FOR DIAGNOSING AND TREATING ALZHEIMER'S DISEASE | BEAUMONT HOSPITAL WILLIAM (US) | 2020-05-28 | — | — | US | claimed |
| WO-2019023239-A1 | METHODS FOR DIAGNOSING AND TREATING ALZHEIMER'S DISEASE | WILLIAM BEAUMONT HOSPITAL (US) | 2019-01-31 | — | — | WO | claimed |
| CN-102516128-A | Synthetic technology of diphenylmethane dicarbamate by adopting Bronsted-Lewis acidic ionic liquid catalysis | UNIV HEBEI TECHNOLOGY | 2012-06-27 | — | — | CN | claimed |
| EP-2173740-A1 | HEME-OXYGENASE INHIBITORS AND USE OF THE SAME IN THE TREATMENT OF CANCER AND DISEASES OF THE CENTRAL NERVOUS SYSTEM | Osta Biotechnologies (CA) | 2010-04-14 | — | — | EP | claimed |
| US-20090176831-A1 | Compounds and Methods for Treating Cancer and Diseases of the Central Nervous System | OSTA BIOTECHNOLOGIES (CA) | 2009-07-09 | — | — | US | claimed |
| WO-2008151437-A1 | HEME-OXYGENASE INHIBITORS AND USE OF THE SAME IN THE TREATMENT OF CANCER AND DISEASES OF THE CENTRAL NERVOUS SYSTEM | OSTA BIOTECHNOLOGIES (CA) | 2008-12-18 | — | — | WO | claimed |
| US-11737463-B2 | Pyridine and pyrazine compounds | BASF SE (DE) | 2023-08-29 | — | — | US | disclosed |
| CN-116332929-A | 3-amido-beta-carboline compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-06-27 | — | — | CN | disclosed |
| CN-113683944-A | Production process of water-bubble-resistant corrosion-resistant stone-like paint | 安徽众雁涂料有限公司 | 2021-11-23 | — | — | CN | disclosed |
| WO-2021129629-A1 | ZESTE ENHANCER HOMOLOGUE 2 INHIBITOR AND USE THEREOF | 四川海思科制药有限公司 | 2021-07-01 | — | — | WO | disclosed |
| US-20200166526-A1 | METHODS FOR DIAGNOSING AND TREATING ALZHEIMER'S DISEASE | BEAUMONT HOSPITAL WILLIAM (US) | 2020-05-28 | — | — | US | disclosed |
| US-20200166526-A1 | METHODS FOR DIAGNOSING AND TREATING ALZHEIMER'S DISEASE | BEAUMONT HOSPITAL WILLIAM (US) | 2020-05-28 | — | — | US | disclosed |
| EP-2917212-B1 | ANTIMICROBIAL AGENTS | UNIV RUTGERS (US) | 2019-06-12 | — | — | EP | disclosed |
| US-20070105919-A1 | adenosine A2A receptor antagonists; N-[4-(2-Furyl)-5-(4-pyridyl)thiazol-2-yl]pyridine-4-carboxamide; treatment of Parkinson's disease, Alzheimer's disease, progressive supranuclear palsy, AIDS encephalopathy, nerve system disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |
| EP-1336612-B1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA (JP) | 2007-01-17 | — | — | EP | disclosed |
| CN-1671662-A | Piperidine derivatives, process for their preparation and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-09-21 | — | — | CN | disclosed |
| EP-0111384-B1 | THIOKETAL SUBSTITUTED N-ALKYL IMIDAZOLES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1987-04-22 | — | — | EP | disclosed |
| US-4489087-A | Spermicidal thioketal substituted N-alkyl imidazoles | SYNTEX (U.S.A.) INC. (US) | 1984-12-18 | — | — | US | disclosed |
| EP-0111384-A1 | Thioketal substituted N-alkyl imidazoles and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1984-06-20 | — | — | EP | disclosed |