SCHEMBL85945

SCHEMBL85945

O=C(Cl)Cn1ccnc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7241523 0.82 ALDH1A1 (0.72)
SCHEMBL77978 0.80
SCHEMBL9706341 0.79 EGLN3 (0.69)
SCHEMBL28119672 0.78 ALDH1A1 (0.96)
SCHEMBL1179222 0.78
SCHEMBL27785516 0.78 ALDH1A1 (0.96)
Hydrochloric Acid SCHEMBL1904485 0.78 ALDH1A1 (0.96)
Bromide SCHEMBL6988476 0.78 ALDH1A1 (0.96)
SCHEMBL412255 0.78
SCHEMBL4603470 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116712754-A Capillary gas chromatography chiral separation column based on cyclodextrin porous liquid 云南师范大学 2023-09-08 CN claimed
CN-111995794-B Cyclodextrin porous liquid material and application thereof 中国石油大学(华东) 2022-07-29 CN claimed
CN-110903442-B Flame-retardant modified corn straw and preparation method thereof 西北民族大学 2022-04-12 CN claimed
CN-110684311-B Modified corn straw flame-retardant degradable foam material and preparation method thereof 西北民族大学 2022-02-11 CN claimed
CN-111995794-A Cyclodextrin porous liquid material and application thereof 中国石油大学(华东) 2020-11-27 CN claimed
CN-110903442-A Flame-retardant modified corn straw and preparation method thereof 西北民族大学 2020-03-24 CN claimed
WO-2025085030-A1 SYNTHESIS OF SEMISYNTHETIC PENICILLIN DERIVATIVES CONTAINING HYDRAZONE-DERIVED THIAZOLIDINE AND IMIDAZOLE RING ERCIYES UNIVERSITESI (TR) 2025-04-24 WO disclosed
WO-2025085030-A1 SYNTHESIS OF SEMISYNTHETIC PENICILLIN DERIVATIVES CONTAINING HYDRAZONE-DERIVED THIAZOLIDINE AND IMIDAZOLE RING ERCIYES UNIVERSITESI (TR) 2025-04-24 WO disclosed
WO-2025085026-A1 SYNTHESIS OF SEMISYNTHETIC PENICILLIN DERIVATIVES CONTAINING HYDRAZONE-DERIVED THIAZOLIDINE AND IMIDAZOLE RING T.C. ERCIYES UNIVERSITESI (TR) 2025-04-24 WO disclosed
WO-2025085026-A1 SYNTHESIS OF SEMISYNTHETIC PENICILLIN DERIVATIVES CONTAINING HYDRAZONE-DERIVED THIAZOLIDINE AND IMIDAZOLE RING T.C. ERCIYES UNIVERSITESI (TR) 2025-04-24 WO disclosed
CN-116712754-A Capillary gas chromatography chiral separation column based on cyclodextrin porous liquid 云南师范大学 2023-09-08 CN disclosed
CN-111995794-B Cyclodextrin porous liquid material and application thereof 中国石油大学(华东) 2022-07-29 CN disclosed
CN-110903442-B Flame-retardant modified corn straw and preparation method thereof 西北民族大学 2022-04-12 CN disclosed
US-7304086-B2 Inhibitors of glutaminyl cyclase PROBIODRUG AG (DE) 2007-12-04 US disclosed
US-20070191366-A1 USE OF EFFECTORS OF GLUTAMINYL AND GLUTAMATE CYCLASES PROBIODRUG AG (DE) 2007-08-16 US disclosed
US-20070099211-A1 Detection of nucleic acid amplification APPLIED BIOSYSTEMS, LLC 2007-05-03 US disclosed
CN-1148346-C Hydrazine derivative - 2004-05-05 CN disclosed
EP-0198325-B1 SUBSTITUTED ANILINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1992-07-15 EP disclosed
US-4891429-A CHEMICAL INTERMEDIATES HOFFMANN-LA ROCHE INC. (US) 1990-01-02 US disclosed
US-4696930-A CARDIOVASCULAR DISORDERS, ANTICOAGULANTS HOFFMANN-LA ROCHE INC. (US) 1987-09-29 US disclosed