Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 10/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL4125191 | 0.88 | ACHE (0.38) | ACHEKDM1ASLC6A2SLC6A4SLC6A3 | |
| Dimethylamine SCHEMBL4112593 | 0.87 | ACHE (0.39) | ACHEKDM1AMAOBAKT1 | |
| Dimethylamine SCHEMBL4120902 | 0.86 | ACHE (0.41) | ACHEKDM1AMAOB | |
| Dimethylamine SCHEMBL4120951 | 0.84 | ACHE (0.60) | ACHE | |
| SCHEMBL4122623 | 0.84 | ACHE (0.37) | ACHEKDM1ASLC6A2SLC6A4SLC6A3 | |
| Dimethylamine SCHEMBL4120455 | 0.84 | ACHE (0.59) | ACHEMAOB | |
| Dimethylamine SCHEMBL4121342 | 0.83 | KDM1A (0.42) | ACHEKDM1AMAOBAKT1KCNH2 | |
| Dimethylamine SCHEMBL4115067 | 0.83 | ACHE (0.47) | ACHEMAOB | |
| Dimethylamine SCHEMBL4115140 | 0.82 | ACHE (0.47) | ACHEMAOB | |
| Dimethylamine SCHEMBL4126427 | 0.82 | SLC6A4 (0.39) | ACHESLC6A2SLC6A4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2017275-A1 | BENZISOXAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | ACHE 3716/4885KDM1A 1437/4885SLC6A2 1758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.