SCHEMBL4122902

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1019967	0.84	SMN1; SMN2 (0.78)	TRPV1MAPTMEN1KMT2ACASP3
	SCHEMBL4915540	0.84	NPC1 (0.76)	TRPV1MAPTMEN1KMT2ACASP3
	SCHEMBL4105986	0.84	RAB9A (0.64)	TRPV1MAPTMEN1KMT2ACASP3
	SCHEMBL4111911	0.83	TRPV1 (0.75)	TRPV1MAPTMEN1KMT2ACASP3
	SCHEMBL14825275	0.83	MAPT (0.69)	TRPV1MAPTMEN1KMT2ACASP3
	SCHEMBL4915756	0.83	MAPT (0.72)	TRPV1MAPTMEN1KMT2ACASP3
	SCHEMBL5157218	0.82	NPC1 (0.59)	MAPTMEN1KMT2ACASP3SENP7
	SCHEMBL11847456	0.81	MAPT (0.72)	MAPTMEN1KMT2ACASP3SENP7
	SCHEMBL5074250	0.81	MEN1 (0.65)	TRPV1MAPTMEN1KMT2ACASP3
	SCHEMBL11007737	0.81	MEN1 (0.61)	TRPV1MAPTMEN1KMT2ACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.