Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409614 | 0.92 | GRIN2B (0.40) | KMT2AGRIA1CACNG8LMNASMN1; SMN2 | |
| SCHEMBL10886037 | 0.84 | KMT2A (0.42) | KMT2ALMNASMN1; SMN2GRIN2BTSHR | |
| SCHEMBL8653715 | 0.82 | GRIA1 (0.48) | KMT2AGRIA1CACNG8SMN1; SMN2GRIN2B | |
| SCHEMBL7928193 | 0.82 | KMT2A (0.41) | KMT2ALMNASMN1; SMN2TSHRAR | |
| SCHEMBL4654446 | 0.82 | RXRA (0.47) | GAA | |
| SCHEMBL10638172 | 0.80 | KMT2A (0.40) | KMT2ALMNASMN1; SMN2TSHRAR | |
| SCHEMBL10639515 | 0.80 | KMT2A (0.40) | KMT2ALMNASMN1; SMN2TSHRAR | |
| SCHEMBL10979488 | 0.80 | KMT2A (0.40) | KMT2ALMNASMN1; SMN2P2RX7TSHR | |
| SCHEMBL10873879 | 0.79 | GRIA1 (0.42) | GRIA1CACNG8GRIN2BP2RX7SLC22A12 | |
| SCHEMBL21603543 | 0.79 | GRIA1 (0.42) | GRIA1CACNG8LMNASMN1; SMN2GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108059590-A | A kind of preparation method of 3- trifluoromethoxies -4- chlorobenzaldehydes | 珠海奥博凯生物医药技术有限公司 | 2018-05-22 | — | — | CN | claimed |
| CN-103012171-B | Preparation method of 4-chloro-5(trifluoromethoxy)-1,2-phenylenediamine | BIOCOMPOUNDS PHARMACEUTICAL INC BPI | 2015-07-22 | — | — | CN | claimed |
| CN-103772160-B | Method for synthesizing trichlorine methoxyl chlorobenzene and trichlorine methoxyl phenylamine | LIU SHIWEI | 2015-02-25 | — | — | CN | claimed |
| CN-103772160-A | Method for synthesizing trichlorine methoxyl chlorobenzene and trichlorine methoxyl phenylamine | LIU SHIWEI | 2014-05-07 | — | — | CN | claimed |
| CN-103012171-A | Preparation method of 4-chloro-5(trifluoromethoxy)-1,2-phenylenediamine | BIOCOMPOUNDS PHARMACEUTICAL INC BPI | 2013-04-03 | — | — | CN | claimed |
| EP-0159388-A2 | Preparation of nuclear chlorinated compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-10-30 | — | — | EP | claimed |
| US-4470930-A | Preparation of nuclear chlorinated aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-11 | — | — | US | claimed |
| CN-116730879-B | Method for selectively synthesizing 4-amino-N- (hetero) aryl sulfonamide compound | SHAANXI NORMAL UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-112521254-B | Preparation method of trifluoromethoxybenzene compound | 金凯(辽宁)生命科技股份有限公司 | 2024-05-17 | — | — | CN | disclosed |
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YROK (US) | 2023-09-19 | — | — | US | disclosed |
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YROK (US) | 2023-09-19 | — | — | US | disclosed |
| CN-116730879-A | Method for selectively synthesizing 4-amino-N- (hetero) aryl sulfonamide compound | 陕西师范大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-116332942-A | Synthesis method of substituted pyrazolo-quinazoline derivative | 合肥工业大学 | 2023-06-27 | — | — | CN | disclosed |
| EP-0147299-A2 | Process for the preparation of benzophenones | RHONE-POULENC CHIMIE (FR) | 1985-07-03 | — | — | EP | disclosed |
| EP-0140783-A2 | Process for the preparation of meta-substituted anilines | RHONE-POULENC CHIMIE (FR) | 1985-05-08 | — | — | EP | disclosed |
| US-4470930-A | Preparation of nuclear chlorinated aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-11 | — | — | US | disclosed |
| US-4465842-A | Preparation of N-benzylimides | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-08-14 | — | — | US | disclosed |
| EP-0066484-B1 | PROCESS FOR THE PREPARATION OF N-BENZYL-SUBSTITUTED IMIDES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-08-08 | — | — | EP | disclosed |
| EP-0113625-A1 | Process for the preparation of trifluoromethylated benzenic compounds | RHONE-POULENC CHIMIE (FR) | 1984-07-18 | — | — | EP | disclosed |
| US-3935258-A | FROM A BENZAMIDE, HYPOHALITE, AMINE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | AFF2, AFF4, AFF1 | KMT2A 349/4885GRIA1 4212/4885CACNG8 4230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.