SCHEMBL4122937

SCHEMBL4122937

Cc1ccccc1C(Cl)(Cl)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
ACHE P22303 3/20 0.39
KCNN4 O15554 4/20 0.38
CYP1A2 P05177 1/20 0.37
KIF11 P52732 1/20 0.36
MAPK1 P28482 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
ALDH1A1 P00352 3/20 0.33
TAAR1 Q96RJ0 1/20 0.32
ALOX15 P16050 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11865116 0.85 TSHR (0.39) TSHRACHECYP1A2KIF11MAPK1
SCHEMBL11858662 0.84 NR3C1 (0.38) TSHRACHEKCNN4KIF11ALDH1A1
SCHEMBL11724522 0.83 TSHR (0.55) TSHRACHEKCNN4CYP1A2MAPK1
SCHEMBL2484316 0.82 TSHR (0.44) TSHRACHEKCNN4CYP1A2KIF11
SCHEMBL3801446 0.82 TSHR (0.44) TSHRACHEKCNN4CYP1A2KIF11
SCHEMBL11867014 0.81 CA4 (0.40) TSHRACHEKIF11MAPK1ALDH1A1
SCHEMBL11859226 0.81 ESR2 (0.39) KIF11ESR2ALDH1A1
SCHEMBL16933920 0.80 TSHR (0.42) TSHRACHEKCNN4CYP1A2KIF11
SCHEMBL11870680 0.79 ACHE (0.39) TSHRACHEKCNN4KIF11GABRA1
SCHEMBL9632116 0.76 TSHR (0.43) TSHRACHEKCNN4KIF11MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1986964-B1 PROCESS FOR ELIMINATING ORGANIC MATTER AND FOR GENERATING ENERGY UNIV AIX MARSEILLE (FR) 2019-03-13 EP disclosed
CN-101311719-B Mono-methyl halogenated diphenyl methane detection method SHENZHEN CT TESTING INTERNAT LTD 2010-08-04 CN disclosed
US-20090235849-A1 PROCESS FOR ELIMINATING ORGANIC MATTER AND FOR GENERATING ENERGY UNIVERSITE DE PROVENCE AIX MARSEILLE 1 (FR) 2009-09-24 US disclosed
CN-101311719-A Mono-methyl halogenated diphenyl methane detection method SHENZHEN CT TESTING INTERNAT L (CN) 2008-11-26 CN disclosed
EP-1986964-A1 PROCESS FOR ELIMINATING ORGANIC MATTER AND FOR GENERATING ENERGY Université de Provence Aix-Marseille 1 (FR) 2008-11-05 EP disclosed
WO-2007096506-A1 PROCESS FOR ELIMINATING ORGANIC MATTER AND FOR GENERATING ENERGY UNIVERSITE DE PROVENCE AIX MARSEILLE 1 (FR) 2007-08-30 WO disclosed
WO-2002042246-A1 METHOD FOR THE PREPARATION OF DICHLORODIARYLMETHANES TESSENDERLO CHEMIE N.V. (BE) 2002-05-30 WO disclosed
US-3985766-A ANTIMYCOTICS BAYER AKTIENGESELLSCHAFT (DT) 1976-10-12 US disclosed