SCHEMBL4122951

SCHEMBL4122951

[CH2]N(C(C)(C)CC)C(C)(C)CC

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2237355 0.69 TSHR (0.43) TSHRTDP1
SCHEMBL3410921 0.67 TSHR (0.40) TSHRTDP1
SCHEMBL3414497 0.67
SCHEMBL16332315 0.65 TSHR (0.32) TSHRTDP1
SCHEMBL1401767 0.64 TSHR (0.38) TSHRTDP1
SCHEMBL5570795 0.64
SCHEMBL9930552 0.64 TSHR (0.38) TSHRTDP1
SCHEMBL14236895 0.64
SCHEMBL3413807 0.64 TSHR (0.38) TSHRTDP1
SCHEMBL3196942 0.64 TSHR (0.38) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090093468-A1 Peptide Deformylase Inhibitors ARPIDA A/S (DK) 2009-04-09 US disclosed
US-20070066672-A1 Benzimidazole derivatives and use thereof as peptide deformylase inhibitors ARPIDA A/S (DK) 2007-03-22 US disclosed
EP-1732907-A1 PEPTIDE DEFORMYLASE INHIBITORS Arpida A/S (DK) 2006-12-20 EP disclosed
WO-2005092872-A1 PEPTIDE DEFORMYLASE INHIBITORS ARPIDA A/S (DK) 2005-10-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066672-A1 Benzimidazole derivatives and use thereof as peptide deformylase inhibitors PDF, MRPL21, PEPD TSHR 2044/4885TDP1 3197/4885
US-20090093468-A1 Peptide Deformylase Inhibitors PDF, PEPD, MRPL21 TSHR 1829/4885TDP1 2070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.