Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4124971 | 0.90 | L3MBTL1 (0.48) | L3MBTL1SIRT2SIRT1RPS6KB1ALDH1A1 | |
| SCHEMBL4133794 | 0.89 | L3MBTL1 (0.61) | L3MBTL1RPS6KB1PTGER4 | |
| SCHEMBL4137916 | 0.86 | MAPT (0.46) | L3MBTL1SIRT2SIRT1RPS6KB1ALDH1A1 | |
| SCHEMBL4118974 | 0.86 | RPS6KB1 (0.44) | L3MBTL1SIRT2SIRT1RPS6KB1ALDH1A1 | |
| SCHEMBL5776100 | 0.86 | SIRT2 (0.45) | L3MBTL1SIRT2SIRT1RPS6KB1ALDH1A1 | |
| SCHEMBL4280453 | 0.85 | SIRT2 (0.48) | L3MBTL1SIRT2SIRT1RPS6KB1ALDH1A1 | |
| SCHEMBL4125616 | 0.84 | BMPR2 (0.44) | L3MBTL1SIRT2SIRT1RPS6KB1TP53 | |
| SCHEMBL4140386 | 0.84 | SIRT2 (0.42) | L3MBTL1SIRT2SIRT1RPS6KB1ALDH1A1 | |
| SCHEMBL4124652 | 0.84 | SIRT2 (0.42) | L3MBTL1SIRT2SIRT1RPS6KB1ALDH1A1 | |
| SCHEMBL4518317 | 0.83 | RPS6KB1 (0.42) | L3MBTL1SIRT2SIRT1RPS6KB1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110724154-A | Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof | 湖北科技学院 | 2020-01-24 | — | — | CN | claimed |
| JP-2007501189-A | — | — | 2007-01-25 | — | — | JP | claimed |
| EP-1651631-A1 | BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE | GENELABS TECHNOLOGIES, INC. (US) | 2006-05-03 | — | — | EP | claimed |
| US-20050187390-A1 | Bicyclic heteroaryl derivatives | GENELABS TECHNOLOGIES, INC. | 2005-08-25 | — | — | US | claimed |
| WO-2005012288-A1 | BICYCLIC IMIDAZOL DERIVATIVES AGAINST FLAVIVIRIDAE | GENELABS TECHNOLOGIES, INC (US) | 2005-02-10 | — | — | WO | claimed |
| JP-4146984-A | — | — | None | — | — | JP | disclosed |
| CN-114502609-A | Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal element | JSR株式会社 | 2022-05-13 | — | — | CN | disclosed |
| CN-114207085-A | Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal element | JSR株式会社 | 2022-03-18 | — | — | CN | disclosed |
| WO-2021070515-A1 | LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL ELEMENT | JSR株式会社 | 2021-04-15 | — | — | WO | disclosed |
| WO-2021049255-A1 | LIQUID CRYSTAL ORIENTATION AGENT, LIQUID CRYSTAL ORIENTATION FILM, AND LIQUID CRYSTAL ELEMENT | JSR株式会社 | 2021-03-18 | — | — | WO | disclosed |
| CN-110724154-B | Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof | 湖北科技学院 | 2020-08-04 | — | — | CN | disclosed |
| CN-110724154-A | Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof | 湖北科技学院 | 2020-01-24 | — | — | CN | disclosed |
| US-5596039-A | FLAME RETARDERS, HEAT RESISTANCE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1997-01-21 | — | — | US | disclosed |
| US-5569726-A | USEFUL IN FLAME-RETARDING, THERMAL STABILIZATION AND COMPATIBILIZATION OF RESINS AND IN THERMOSETTING MOLDING COMPOSITIONS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-10-29 | — | — | US | disclosed |
| US-5545702-A | THERMOSETTING RESIN COMPOSITION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-08-13 | — | — | US | disclosed |
| US-5536795-A | ADHESIVES AND PAINTS AND FIREPROOFING THERMOSETTING RESINS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5480947-A | N-METHYLOL DIGUANAMINES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0634406-A1 | DIGUANAMINE, AND PRODUCTION, DERIVATIVE AND USE THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-01-18 | — | — | EP | disclosed |
| US-5162087-A | Acrylic-Maleimide Interpolymer, Metallic Layer Particles | SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| JP-H04146984-A | RESIN FOR ADHESIVE AND ADHESIVE CONTAINING THE RESIN | SOKEN KAGAKU KK | 1992-05-20 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187390-A1 | Bicyclic heteroaryl derivatives | HAVCR2, MAVS, ZC3HAV1 | L3MBTL1 1221/4885SIRT2 1825/4885SIRT1 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.