SCHEMBL4123540

SCHEMBL4123540

CC(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 1.00
KDM4E B2RXH2 3/20 0.74
KMT2A Q03164 3/20 0.74
ALDH1A1 P00352 3/20 0.74
MEN1 O00255 2/20 0.68
MAPT P10636 1/20 0.68
POLB P06746 2/20 0.66
TP53 P04637 1/20 0.66
HPGD P15428 1/20 0.66
AMY1A P0DUB6 1/20 0.65
MAPK1 P28482 1/20 0.65
TDP1 Q9NUW8 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10031570 0.86 L3MBTL1 (0.75) L3MBTL1KDM4EKMT2AALDH1A1MEN1
SCHEMBL13409107 0.85 FASN (0.83) L3MBTL1KMT2AALDH1A1MEN1POLB
SCHEMBL547543 0.84 KDM4E (1.00) L3MBTL1KDM4EKMT2AALDH1A1MEN1
SCHEMBL31195203 0.84 L3MBTL1 (0.72) L3MBTL1KDM4EKMT2AALDH1A1MEN1
SCHEMBL17592974 0.82 L3MBTL1 (0.69) L3MBTL1KDM4EKMT2AALDH1A1MAPK1
SCHEMBL12793423 0.82 L3MBTL1 (0.69) L3MBTL1KDM4EKMT2AALDH1A1MEN1
SCHEMBL5560388 0.81 L3MBTL1 (0.68) L3MBTL1KDM4EKMT2AALDH1A1MEN1
SCHEMBL29277100 0.81 L3MBTL1 (0.68) L3MBTL1KDM4EKMT2AALDH1A1MEN1
SCHEMBL17593260 0.81 ALDH1A1 (0.71) L3MBTL1KDM4EKMT2AALDH1A1MEN1
SCHEMBL13771587 0.81 ALDH1A1 (0.73) L3MBTL1KDM4EKMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118032981-A Method for extracting sulfonamide antibiotics from plant tissues and application thereof 云南省热带作物科学研究所 2024-05-14 CN disclosed
WO-2017156181-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS, INC. (US) 2017-09-14 WO disclosed
WO-2017156181-A1 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF RAZE THERAPEUTICS, INC. (US) 2017-09-14 WO disclosed
EP-2641738-B1 Planographic printing plate precursor and method for producing a planographic printing plate FUJIFILM CORP (JP) 2016-01-20 EP disclosed
EP-2080616-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-11-27 EP disclosed
EP-2106907-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-10-16 EP disclosed
EP-2641738-A2 Method of producing planographic printing plate and planographic printing plate Fujifilm Corporation (JP) 2013-09-25 EP disclosed
US-20090253071-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-08 US disclosed
EP-2106907-A2 Planographic printing plate precursor FUJIFILM Corporation (JP) 2009-10-07 EP disclosed
EP-2080616-A1 Planographic printing plate precursor Fujifilm Corporation (JP) 2009-07-22 EP disclosed