SCHEMBL4123829

SCHEMBL4123829

C[S+]([O-])c1ccc2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 0.44
TDP1 Q9NUW8 1/20 0.44
CYP1A2 P05177 4/20 0.41
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
LMNA P02545 1/20 0.38
UGT2B7 P16662 1/20 0.38
LPL P06858 1/20 0.37
LIPG Q9Y5X9 1/20 0.37
ALOX12 P18054 1/20 0.36
ATM Q13315 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29450253 1.00 CYP2A6 (0.44) CYP2A6TDP1CYP1A2CA1CA2
SCHEMBL30047516 1.00 CYP2A6 (0.44) CYP2A6TDP1CYP1A2CA1CA2
SCHEMBL28906946 1.00 CYP2A6 (0.44) CYP2A6TDP1CYP1A2CA1CA2
SCHEMBL15109051 1.00 CYP2A6 (0.44) CYP2A6TDP1CYP1A2CA1CA2
SCHEMBL12748739 0.81 CYP2A6 (0.48) CYP2A6TDP1CYP1A2CA1CA2
SCHEMBL246506 0.81 CYP2A6 (0.48) CYP2A6TDP1CYP1A2CA1CA2
SCHEMBL29404511 0.81 CYP2A6 (0.48) CYP2A6TDP1CYP1A2CA1CA2
SCHEMBL2785643 0.81 CYP2A6 (0.42) CYP2A6TDP1CYP1A2CA1CA2
SCHEMBL16288483 0.80 CYP1A2 (0.56) CYP2A6TDP1CYP1A2ALDH1A1HSD17B10
SCHEMBL16288482 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115044566-B Cyclohexanone monooxygenase mutant and application thereof 江南大学 2023-05-02 CN claimed
CN-115044566-A Cyclohexanone monooxygenase mutant and application thereof 江南大学 2022-09-13 CN claimed
CN-117486662-A Method for synthesizing sulfoxide compound by heterogeneous catalysis 成都理工大学 2024-02-02 CN disclosed
WO-2023115327-A1 PYRIDO RING COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATION 中国药科大学 2023-06-29 WO disclosed
CN-115305243-B Baeyer-Villiger monooxygenase mutant and application thereof 江南大学 2023-06-02 CN disclosed
CN-115044566-B Cyclohexanone monooxygenase mutant and application thereof 江南大学 2023-05-02 CN disclosed
CN-115305243-A Baeyer-Villiger monooxygenase mutant and application thereof 江南大学 2022-11-08 CN disclosed
CN-115044566-A Cyclohexanone monooxygenase mutant and application thereof 江南大学 2022-09-13 CN disclosed
WO-2018065611-A1 2-AMINO-N-(ARYLSULFINYL)-ACETAMIDE COMPOUNDS AS INHIBITORS OF BACTERIAL AMINOACYL-TRNA SYNTHETASE Oxford Drug Design Limited (GB) 2018-04-12 WO disclosed
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE SAN-APRO LIMITED (JP) 2009-06-25 US disclosed
EP-1953139-A1 METHOD FOR PRODUCING FLUORINATED SULFONIUM ALKYLFLUOROPHOSPHATE San-Apro Ltd. (JP) 2008-08-06 EP disclosed
US-3987191-A (ORGANOSULFINYLMETHYL)TRI-ORGANOTIN ACARICIDAL COMPOSITIONS AND METHODS OF USE THE PROCTER & GAMBLE COMPANY (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE ARSA, SCO2, DOHH CYP2A6 563/4885TDP1 4043/4885CYP1A2 583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.