Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9934740 | 0.71 | NTRK1 (0.31) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL422300 | 0.71 | CCR1 (0.44) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL30060196 | 0.71 | CCR1 (0.44) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL30521461 | 0.69 | ALDH1A1 (0.38) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL25805124 | 0.69 | ALDH1A1 (0.38) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL30540473 | 0.69 | MAP3K14 (0.47) | NTRK1LTKNTRK2CLK4 | |
| SCHEMBL30521562 | 0.69 | ELANE (0.31) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL5463111 | 0.68 | NTRK1 (0.33) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL21388633 | 0.67 | LMNA (0.37) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL20674257 | 0.67 | CHEK1 (0.34) | NTRK1LTKTYRO3NTRK2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149495-A1 | COMPOUNDS | RICHTER GEDEON NYRT. (HU) | 2009-06-11 | — | — | US | disclosed |
| CN-101341153-A | Novel compounds | RICHTER GEDEON NYRT (HU) | 2009-01-07 | — | — | CN | disclosed |
| EP-1963336-A1 | NEW COMPOUNDS | Richter Gedeon NYRT (HU) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007072094-A1 | NEW COMPOUNDS | RICHTER GEDEON NYRT. (HU) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149495-A1 | COMPOUNDS | GRM3, GRM5, GRM1 | NTRK1 321/4885LTK 1734/4885TYRO3 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.