SCHEMBL4124154

SCHEMBL4124154

c1ccc(-c2cc(-c3ccccn3)c(-c3ccccc3)c(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 2/20 0.47
KDM4E B2RXH2 7/20 0.46
LMNA P02545 6/20 0.46
CCR1 P32246 3/20 0.46
CCR5 P51681 3/20 0.46
CCR8 P51685 3/20 0.46
CYP1A2 P05177 1/20 0.46
POLB P06746 1/20 0.46
METAP1 P53582 1/20 0.46
BLM P54132 1/20 0.46
HIF1A Q16665 1/20 0.46
DOHH Q9BU89 1/20 0.46
P4HTM Q9NXG6 1/20 0.46
CYP2A6 P11509 1/20 0.43
KDR P35968 1/20 0.42
RAB9A P51151 7/20 0.41
NPC1 O15118 6/20 0.41
SMN1; SMN2 Q16637 6/20 0.41
TP53 P04637 5/20 0.41
PKM P14618 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4913073 0.91 TGFBR1 (0.46) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL11965542 0.91 TGFBR1 (0.49) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL12932644 0.89 MEN1 (0.43) TGFBR1KDM4EPOLBMETAP1RAB9A
SCHEMBL3892684 0.88 TGFBR1 (0.44) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL12932630 0.88 MEN1 (0.43) TGFBR1KDM4EPOLBMETAP1RAB9A
SCHEMBL31618894 0.87 TGFBR1 (0.46) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL17320276 0.87 TGFBR1 (0.49) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL28954742 0.86 KDM4E (0.52) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL22956100 0.86 TGFBR1 (0.43) TGFBR1KDM4ELMNACCR1CCR5
SCHEMBL12932649 0.85 CYP1A2 (0.40) TGFBR1KDM4ELMNACYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101146814-B Solution processed organometallic complexes and their use in electroluminescent devices AGENCY SCIENCE TECH & RES 2013-01-02 CN disclosed
US-8242488-B2 Organic electroluminescent element, display device, and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-08-14 US disclosed
US-8242488-B2 Organic electroluminescent element, display device, and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-08-14 US disclosed
US-20100207105-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2010-08-19 US disclosed
US-20100207105-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2010-08-19 US disclosed
US-20090123720-A1 SOLUTION PROCESSED ORGANOMETALLIC COMPLEXES AND THEIR USE IN ELECTROLUMINESCENT DEVICES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-05-14 US disclosed
US-20090123720-A1 SOLUTION PROCESSED ORGANOMETALLIC COMPLEXES AND THEIR USE IN ELECTROLUMINESCENT DEVICES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-05-14 US disclosed
US-20090123720-A1 SOLUTION PROCESSED ORGANOMETALLIC COMPLEXES AND THEIR USE IN ELECTROLUMINESCENT DEVICES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-05-14 US disclosed
US-20080067922-A1 Organic Electroluminescent Device ENDO AYATAKA 2008-03-20 US disclosed
US-20080067922-A1 Organic Electroluminescent Device ENDO AYATAKA 2008-03-20 US disclosed
CN-101146814-A Solution processed organometallic complexes and their use in electroluminescent devices AGENCY SCIENCE TECH & RES (SG) 2008-03-19 CN disclosed
EP-1809077-A2 ORGANIC ELECTROLUMINESCENT ELEMENT Japan Science and Technology Agency (JP) 2007-07-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123720-A1 SOLUTION PROCESSED ORGANOMETALLIC COMPLEXES AND THEIR USE IN ELECTROLUMINESCENT DEVICES BMI1, PCNA, DNMT1 TGFBR1 3088/4885KDM4E 1046/4885LMNA 3690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.