Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
| ▸ | CCR8 | P51685 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22956076 | 0.94 | DHODH (0.46) | TGFBR1CYP2A6LMNACYP1A2CCR1 | |
| SCHEMBL4124154 | 0.91 | TGFBR1 (0.47) | TGFBR1CYP2A6LMNACYP1A2CCR1 | |
| SCHEMBL3892684 | 0.90 | TGFBR1 (0.44) | TGFBR1CYP2A6LMNACYP1A2CCR1 | |
| SCHEMBL9974907 | 0.89 | LMNA (0.52) | TGFBR1CYP2A6LMNACYP1A2CCR1 | |
| SCHEMBL22956100 | 0.88 | TGFBR1 (0.43) | TGFBR1CYP2A6LMNACYP1A2CCR1 | |
| SCHEMBL22956079 | 0.88 | DHODH (0.42) | TGFBR1CYP2A6LMNACYP1A2CCR1 | |
| SCHEMBL9974919 | 0.87 | LMNA (0.50) | TGFBR1CYP2A6LMNACYP1A2CCR1 | |
| SCHEMBL22956108 | 0.87 | TGFBR1 (0.42) | TGFBR1CYP2A6LMNACYP1A2CCR1 | |
| SCHEMBL28899126 | 0.86 | TGFBR1 (0.44) | TGFBR1CYP2A6LMNACYP1A2CCR1 | |
| SCHEMBL22956077 | 0.86 | KDR (0.41) | TGFBR1CYP2A6LMNACYP1A2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9078330-B2 | Highly branched dendrimers | ISIS INNOVATION LIMITED (GB) | 2015-07-07 | — | — | US | disclosed |
| US-20080211391-A1 | Highly Branched Dendrimers | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080211391-A1 | Highly Branched Dendrimers | ITGB1, PICALM, BTN3A1 | TGFBR1 487/4885CYP2A6 4510/4885LMNA 977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.