SCHEMBL4124461

SCHEMBL4124461

CCC(=CC#N)c1ccc2c(c1)C(CC)(CC)OC(=O)N2

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ELOVL6 Q9H5J4 3/20 0.38
PGR P06401 16/20 0.37
AR P10275 3/20 0.36
NR3C1 P04150 2/20 0.36
NR3C2 P08235 2/20 0.36
CYP46A1 Q9Y6A2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4124453 1.00 ELOVL6 (0.38) ELOVL6PGRARNR3C1NR3C2
SCHEMBL4124456 1.00 ELOVL6 (0.38) ELOVL6PGRARNR3C1NR3C2
SCHEMBL4126737 0.92 ELOVL6 (0.37) ELOVL6PGRARNR3C1NR3C2
SCHEMBL4126731 0.92 ELOVL6 (0.37) ELOVL6PGRARNR3C1NR3C2
SCHEMBL4126741 0.92 ELOVL6 (0.37) ELOVL6PGRARNR3C1NR3C2
SCHEMBL4113817 0.88 ELOVL6 (0.38) ELOVL6PGRARNR3C1NR3C2
SCHEMBL4113810 0.88 ELOVL6 (0.38) ELOVL6PGRARNR3C1NR3C2
SCHEMBL4125414 0.88 PGR (0.49) PGRARNR3C1NR3C2
SCHEMBL4113818 0.88 ELOVL6 (0.38) ELOVL6PGRARNR3C1NR3C2
SCHEMBL4125416 0.88 PGR (0.49) PGRARNR3C1NR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090197878-A1 SUBSTITUTED BENZO[d][1,3]OXAZIN-2(4H)-ONES AND RELATED DERIVATIVES AND THEIR USES FOR MODULATING THE PROGESTERONE RECEPTOR WYETH (US) 2009-08-06 US claimed
US-20090197878-A1 SUBSTITUTED BENZO[d][1,3]OXAZIN-2(4H)-ONES AND RELATED DERIVATIVES AND THEIR USES FOR MODULATING THE PROGESTERONE RECEPTOR WYETH (US) 2009-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090197878-A1 SUBSTITUTED BENZO[d][1,3]OXAZIN-2(4H)-ONES AND RELATED DERIVATIVES AND THEIR USES FOR MODULATING THE PROGESTERONE RECEPTOR GNRHR, GPER1, FSHR ELOVL6 3079/4885PGR 4/4885AR 103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.