SCHEMBL4124502

SCHEMBL4124502

O=C(O)c1ccc(OC(=O)c2ccc3cc(OC(=O)c4ccc(C(=O)Oc5ccc(O)cc5)cc4)ccc3c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.57
MEN1 O00255 5/20 0.57
MAPT P10636 2/20 0.57
TDP1 Q9NUW8 1/20 0.57
ESR1 P03372 3/20 0.51
CA12 O43570 3/20 0.50
CA9 Q16790 3/20 0.50
CASP3 P42574 2/20 0.50
SENP8 Q96LD8 2/20 0.50
SENP7 Q9BQF6 2/20 0.50
SENP6 Q9GZR1 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA3 P07451 1/20 0.50
TYR P14679 1/20 0.50
DRD1 P21728 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4138214 0.98 KMT2A (0.54) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL5023168 0.96 KMT2A (0.53) KMT2AMEN1MAPTTDP1ESR1
Paraben SCHEMBL5260518 0.95 CA12 (0.52) KMT2AMEN1MAPTTDP1ESR1
Terephthalic Acid SCHEMBL4935828 0.95 CA12 (0.52) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL5024613 0.95 CA1 (0.55) KMT2AMEN1MAPTTDP1ESR1
Paraben SCHEMBL5079569 0.94 CA1 (0.53) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL9793342 0.94 KMT2A (0.60) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL5023133 0.93 KDM4E (0.50) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL2345023 0.91 HSD17B10 (0.51) KMT2AMEN1MAPTTDP1ESR1
SCHEMBL6394400 0.91 HSD17B10 (0.51) KMT2AMEN1MAPTTDP1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1983020-B1 METHOD FOR MODIFICATION OF LIQUID CRYSTAL POLYMER LEF TECHNOLOGY INC (JP) 2014-05-07 EP disclosed
US-7608371-B2 Irradiating polyesters with laser beam having pulse width of 10-12 seconds or less to improve physical strength; abrasion resistance LEF TECHNOLOGY, INC. (JP) 2009-10-27 US disclosed
US-20090048362-A1 Method of Modifying Liquid Crystal Polymers LEF TECHNOLOGY, INC. (JP) 2009-02-19 US disclosed
EP-1983020-A1 METHOD FOR MODIFICATION OF LIQUID CRYSTAL POLYMER LEF Technology Inc. (JP) 2008-10-22 EP disclosed
EP-1645584-B1 Method for manufacturing wholly aromatic liquid-crystalline polyester resin UENO SEIYAKU OYO KENKYUJO KK (JP) 2008-06-18 EP disclosed
US-7335318-B2 Method for manufacturing wholly aromatic liquid-crystalline polyester resin KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2008-02-26 US disclosed
US-20060084747-A1 Method for manufacturing wholly aromatic liquid-crystalline polyester resin KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO 2006-04-20 US disclosed
EP-1645584-A1 Method for manufacturing wholly aromatic liquid-crystalline polyester resin KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2006-04-12 EP disclosed