SCHEMBL4124524

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13045909	0.84	HSD17B10 (0.56)	ALDH1A1HPGDCCNE2CCNE1CDK2
	SCHEMBL14817806	0.80	ALDH1A1 (0.65)	ALDH1A1HPGDHSD17B10NPC1RAB9A
	SCHEMBL13326964	0.78	HSD17B10 (0.50)	ALDH1A1HPGDCCNE2CCNE1CDK2
	SCHEMBL7515266	0.77	HSD17B10 (0.49)	ALDH1A1HPGDCCNE2CCNE1CDK2
	SCHEMBL30702637	0.74	ALDH1A1 (0.70)	ALDH1A1HPGDHSD17B10NPC1RAB9A
	SCHEMBL2307143	0.74	ALDH1A1 (0.70)	ALDH1A1HPGDHSD17B10NPC1RAB9A
	SCHEMBL27561971	0.74	HTR2C (0.51)	ALDH1A1HPGDHSD17B10POLBRIPK1
	SCHEMBL30606199	0.74	HSD17B10 (0.47)	ALDH1A1HPGDHSD17B10POLBKDM4E
	SCHEMBL5515435	0.74	HTR2C (0.52)	HTR2C
	SCHEMBL17133909	0.74	GRM7 (0.46)	ALDH1A1HPGDCREBBPKDM4EHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.