Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 5/20 | 0.74 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 10/20 | 0.72 |
| ▸ | RAB9A | P51151 | 10/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.72 |
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.72 |
| ▸ | RELA | Q04206 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | LCK | P06239 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27093077 | 0.91 | DYRK1A (0.67) | DYRK1ADYRK1BNPC1RAB9AKMT2A | |
| SCHEMBL27093078 | 0.87 | KDR (0.75) | DYRK1ADYRK1BNPC1RAB9AKMT2A | |
| SCHEMBL8290119 | 0.87 | DYRK1A (0.62) | DYRK1ADYRK1BNPC1RAB9AKMT2A | |
| SCHEMBL11724806 | 0.85 | DYRK1A (1.00) | DYRK1ADYRK1BNPC1RAB9AKMT2A | |
| SCHEMBL17001367 | 0.84 | DYRK1A (0.74) | DYRK1ADYRK1BNPC1RAB9AKMT2A | |
| SCHEMBL18824277 | 0.84 | DYRK1A (0.74) | DYRK1ADYRK1BNPC1RAB9AKMT2A | |
| SCHEMBL26034949 | 0.84 | DYRK1A (0.61) | DYRK1ADYRK1BNPC1RAB9AKMT2A | |
| SCHEMBL2245925 | 0.84 | NPC1 (0.79) | DYRK1ADYRK1BNPC1RAB9AKMT2A | |
| SCHEMBL21568324 | 0.84 | DYRK1A (0.58) | DYRK1ADYRK1BNPC1RAB9AKMT2A | |
| SCHEMBL31206312 | 0.84 | DYRK1A (0.62) | DYRK1ANPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | CNR1, CNR2, OPRL1 | DYRK1A 2359/4885DYRK1B 2003/4885NPC1 927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.