Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 11/20 | 1.00 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.72 |
| ▸ | RELA | Q04206 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | SNCA | P37840 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | LCK | P06239 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22905 | 0.91 | DYRK1A (1.00) | DYRK1ADYRK1BNPC1MAPTRAB9A | |
| SCHEMBL4124786 | 0.85 | DYRK1A (0.74) | DYRK1ADYRK1BNPC1MAPTRAB9A | |
| SCHEMBL18824277 | 0.85 | DYRK1A (0.74) | DYRK1ADYRK1BNPC1MAPTRAB9A | |
| SCHEMBL17001367 | 0.85 | DYRK1A (0.74) | DYRK1ADYRK1BNPC1MAPTRAB9A | |
| SCHEMBL1143751 | 0.84 | NPC1 (1.00) | DYRK1ADYRK1BNPC1MAPTRAB9A | |
| SCHEMBL11728977 | 0.84 | NPC1 (0.73) | DYRK1ADYRK1BNPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL28640786 | 0.83 | NPC1 (0.97) | DYRK1ADYRK1BNPC1MAPTRAB9A | |
| SCHEMBL544349 | 0.83 | DYRK1A (0.75) | DYRK1ADYRK1BHSD17B10HSD17B1HSD17B2 | |
| SCHEMBL29788 | 0.82 | HSD17B1 (0.82) | DYRK1ADYRK1BNPC1MAPTRAB9A | |
| SCHEMBL23256870 | 0.82 | DYRK1A (0.70) | DYRK1ADYRK1BNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046770-A | IMMUNE REGULANTS | ELI LILLY AND COMPANY (US) | 1977-09-06 | — | — | US | disclosed |