SCHEMBL41250

SCHEMBL41250

[CH2]c1cc(OC)cc(OC)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.69
CYP1A1 P04798 7/20 0.50
CYP1B1 Q16678 7/20 0.50
CYP1A2 P05177 4/20 0.44
CYP3A4 P08684 3/20 0.44
CYP2E1 P05181 2/20 0.44
CYP2C8 P10632 2/20 0.44
CYP2D6 P10635 2/20 0.44
CYP2A6 P11509 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP4B1 P13584 2/20 0.44
CYP2B6 P20813 2/20 0.44
CYP3A5 P20815 2/20 0.44
CYP2A7 P20853 2/20 0.44
CYP3A7 P24462 2/20 0.44
CYP2F1 P24903 2/20 0.44
CYP2C18 P33260 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP2J2 P51589 2/20 0.44
CYP4F2 P78329 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2809096 0.94 ALDH1A1 (0.59) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
Magnesium Chloride Anhydrous SCHEMBL27723160 0.92 ALDH1A1 (0.58) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL27689508 0.89 ALDH1A1 (0.55) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL16958828 0.84 ALDH1A1 (0.48) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL10979139 0.83 ESR1 (0.50) ALDH1A1CYP1A1CYP1B1CYP3A4ABL1
SCHEMBL16957016 0.83 ALDH1A1 (0.48) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
1,3,5-Trimethoxybenzene SCHEMBL28493 0.83 ALDH1A1 (1.00) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL7667026 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL6978504 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL3397500 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2423 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024133200-A1 P2X3 RECEPTOR ANTAGONISTS RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) 2024-06-27 WO claimed
EP-4389746-A2 P2X3 RECEPTOR ANTAGONISTS Recordati Industria Chimica E Farmaceutica SPA (IT) 2024-06-26 EP claimed
CN-118239883-A Preparation method of lysine-specific demethylase 1 (LSD 1) inhibitor 江苏联环药业股份有限公司 2024-06-25 CN claimed
CN-118206417-A Cobalt catalytic dehalogenation deuteration method 中国科学院大连化学物理研究所 2024-06-18 CN claimed
US-11999732-B2 P2X3 receptor antagonists RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA SPA (IT) 2024-06-04 US claimed
CN-116284021-B Compounds having therapeutic effect on bladder cancer 湖南大学 2024-04-02 CN claimed
EP-3606528-B1 TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF BROAD INST INC (US) 2023-10-18 EP claimed
CN-112707899-B Preparation method of quininol 东莞市东阳光动物保健药品有限公司 2023-10-17 CN claimed
CN-116284021-A Compounds having therapeutic effect on bladder cancer 湖南大学 2023-06-23 CN claimed
EP-4178959-A1 NITROGEN HETEROCYCLIC CYTOKININ DERIVATIVES, COMPOSITIONS CONTAINING THESE DERIVATIVES AND USE THEREOF Univerzita Palackého v Olomouci (CZ) 2023-05-17 EP claimed
EP-0552765-B1 Benzimidazoles, pharmaceutical compositions containing them and process for their preparation THOMAE GMBH DR K (DE) 1996-08-14 EP claimed
EP-0709375-A2 Therapeutic heterocycles ZENECA LIMITED (GB) 1996-05-01 EP claimed
EP-0552765-A1 Benzimidazoles, pharmaceutical compositions containing them and process for their preparation Dr. Karl Thomae GmbH (DE) 1993-07-28 EP claimed
US-4735937-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-04-05 US claimed
EP-0246735-A1 Heterocyclic compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-11-25 EP claimed
US-4707161-A Lightfastness of dyeings obtained with acid dyes or metal complex dyes on polyamides: treatment with copper hydroxamates BASF AKTIENGESELLSCHAFT (DE) 1987-11-17 US claimed
US-4430498-A 8-Oxo-5-thia-1-azabicyclo(4,2,0)oct-2-ene compounds CIBA-GEIGY CORPORATION (US) 1984-02-07 US claimed
US-4115643-A Process for 3-chloro cephalosporins ELI LILLY AND COMPANY (US) 1978-09-19 US claimed
US-4008229-A Halo substituted β-lactam antibiotics ELI LILLY AND COMPANY (US) 1977-02-15 US claimed
US-4008228-A Process for preparing 3-methyl-3-cephem antibiotics ELI LILLY AND COMPANY (US) 1977-02-15 US claimed