SCHEMBL2809096

SCHEMBL2809096

[CH2]c1cc([CH2])cc(OC)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.59
CYP1A1 P04798 6/20 0.43
CYP1B1 Q16678 6/20 0.43
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA12 O43570 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CYP3A4 P08684 3/20 0.42
CYP1A2 P05177 4/20 0.39
CYP2A6 P11509 3/20 0.39
CYP2E1 P05181 2/20 0.39
CYP2C8 P10632 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP4B1 P13584 2/20 0.39
CYP2B6 P20813 2/20 0.39
CYP3A5 P20815 2/20 0.39
CYP2A7 P20853 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL41250 0.94 ALDH1A1 (0.69) ALDH1A1CYP1A1CYP1B1CA1CA2
Magnesium Chloride Anhydrous SCHEMBL27723160 0.86 ALDH1A1 (0.58) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL27689508 0.84 ALDH1A1 (0.55) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL16958828 0.84 ALDH1A1 (0.48) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL7667026 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL3397500 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL6978504 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL27983892 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL16955152 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL16956418 0.78 CA1 (0.42) ALDH1A1CYP1A1CYP1B1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4888032-A USEFUL FOR OXYGEN SCAVENGING AND SEPARATING OXYGEN FROM AIR THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1989-12-19 US claimed
US-20100240713-A1 AROMATIC AND HETEROAROMATIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS XENON PHARMACEUTICALS INC. (CA) 2010-09-23 US disclosed
US-4888032-A USEFUL FOR OXYGEN SCAVENGING AND SEPARATING OXYGEN FROM AIR THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1989-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240713-A1 AROMATIC AND HETEROAROMATIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS SLC40A1, PAH, FECH ALDH1A1 749/4885CYP1A1 39/4885CYP1B1 59/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.