Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 5/20 | 0.70 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.58 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CCNC | P24863 | 1/20 | 0.51 |
| ▸ | CDK8 | P49336 | 1/20 | 0.51 |
| ▸ | IDH1 | O75874 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4118089 | 0.87 | KCNQ3 (0.72) | KCNQ3KCNQ2RAB9AKCNE1KCNQ1 | |
| SCHEMBL6361424 | 0.85 | KCNQ3 (0.64) | KCNQ3KCNQ2RAB9AKCNE1KCNQ1 | |
| SCHEMBL30568974 | 0.85 | KCNQ3 (0.64) | KCNQ3KCNQ2RAB9AKCNE1KCNQ1 | |
| SCHEMBL2303285 | 0.82 | KCNQ3 (0.80) | KCNQ3KCNQ2RAB9AKDM4EKCNE1 | |
| SCHEMBL27910562 | 0.81 | EPHX1 (0.71) | KCNQ3KCNQ2RAB9AKCNE1KCNQ1 | |
| SCHEMBL22125215 | 0.80 | SMARCA2 (0.69) | KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL4113264 | 0.79 | IDH1 (0.69) | RAB9AALDH1A1NPC1SMN1; SMN2POLB | |
| SCHEMBL27954471 | 0.79 | MEN1 (0.70) | KCNQ3KCNQ2RAB9AKCNE1KCNQ1 | |
| SCHEMBL27954439 | 0.78 | ALDH1A1 (0.64) | KCNQ3KCNQ2RAB9AKCNE1KCNQ1 | |
| SCHEMBL22092668 | 0.78 | KCNQ3 (0.71) | KCNQ3KCNQ2RAB9AKCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | CNR1, CNR2, OPRL1 | KCNQ3 2409/4885KCNQ2 1940/4885RAB9A 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.