Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.63 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.63 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.52 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113462 | 0.87 | MAPT (0.73) | MEN1MAPTKMT2AALDH1A1KCNJ6 | |
| SCHEMBL30606801 | 0.84 | MAPT (0.87) | MEN1MAPTKMT2AALDH1A1KCNJ6 | |
| SCHEMBL29580531 | 0.84 | MAPT (0.87) | MEN1MAPTKMT2AALDH1A1KCNJ6 | |
| SCHEMBL4112467 | 0.84 | MAPT (0.68) | MEN1MAPTKMT2AALDH1A1KCNJ6 | |
| SCHEMBL4117070 | 0.83 | MAPT (0.80) | MEN1MAPTKMT2AALDH1A1KCNJ6 | |
| SCHEMBL4118553 | 0.82 | NPC1 (0.69) | MEN1MAPTKMT2AALDH1A1NPC1 | |
| SCHEMBL4115751 | 0.81 | NPC1 (0.67) | MEN1MAPTKMT2AKCNJ6KCNJ5 | |
| SCHEMBL4122903 | 0.81 | NPC1 (0.71) | MEN1MAPTKMT2AKCNJ6KCNJ5 | |
| SCHEMBL7248947 | 0.81 | MAPT (1.00) | MEN1MAPTKMT2AALDH1A1KCNJ6 | |
| SCHEMBL4115616 | 0.80 | NPC1 (0.65) | MEN1MAPTKMT2AALDH1A1KCNJ6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | NEUROGEN CORPORATION | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239841-A1 | Diaryl Ureas as CB1 Antagonists | CNR1, CNR2, OPRL1 | MEN1 3273/4885MAPT 1654/4885KMT2A 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.