Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL4121892 | 0.91 | GPR119 (0.45) | ACHESLC6A4HRH3 | |
| Dimethylamine SCHEMBL4120902 | 0.90 | ACHE (0.41) | ACHEBCHEKDM1AMAOAMAOB | |
| Dimethylamine SCHEMBL4112450 | 0.89 | ACHE (0.42) | ACHEBCHEKDM1AMAOAMAOB | |
| SCHEMBL4126868 | 0.87 | ACHE (0.42) | ACHESLC6A4HRH3BCHEPOLB | |
| SCHEMBL4131099 | 0.86 | ACHE (0.42) | ACHESLC6A4HRH3BCHEPOLB | |
| Dimethylamine SCHEMBL4134383 | 0.86 | ACHE (0.43) | ACHEBCHEKDM1A | |
| Dimethylamine SCHEMBL4134327 | 0.86 | ACHE (0.61) | ACHEBCHE | |
| Dimethylamine SCHEMBL4112605 | 0.86 | ACHE (0.42) | ACHESLC6A4HRH3BCHEMAOA | |
| Dimethylamine SCHEMBL4125191 | 0.86 | ACHE (0.38) | ACHESLC6A4HRH3CYP11B1CYP11B2 | |
| Dimethylamine SCHEMBL4126864 | 0.85 | ACHE (0.39) | ACHEBCHEKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2017275-A1 | BENZISOXAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | ACHE 3716/4885SLC6A4 1398/4885HRH3 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.