SCHEMBL4127900

SCHEMBL4127900

ClC(SSCc1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
IDO1 P14902 4/20 0.35
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
POLB P06746 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CTSL P07711 1/20 0.33
CTSB P07858 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
MAOB P27338 1/20 0.33
S100A4 P26447 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2171639 0.79 TSHR (0.42) TSHRIDO1NOS3NOS1NOS2
SCHEMBL766520 0.78 TSHR (0.55) TSHRSLC6A2SLC6A4SLC6A3
SCHEMBL17662325 0.72 SLC6A4 (0.42) IDO1NOS3NOS1NOS2POLB
Dibenzyl Disulfide SCHEMBL160895 0.72 HSD17B10 (0.52) TSHRIDO1NOS3NOS1NOS2
Dibenzyl Disulfide SCHEMBL16332737 0.72 HSD17B10 (0.52) TSHRIDO1NOS3NOS1NOS2
Dibenzyl Disulfide SCHEMBL31120434 0.70 HSD17B10 (0.50) TSHRIDO1NOS3NOS1NOS2
Dibenzyl Disulfide SCHEMBL32679343 0.70 HSD17B10 (0.50) TSHRIDO1NOS3NOS1NOS2
Dibenzyl Disulfide SCHEMBL28928181 0.70 ALDH1A1 (0.50) TSHRIDO1NOS3NOS1NOS2
Dibenzyl Disulfide SCHEMBL30254005 0.70 HSD17B10 (0.50) TSHRIDO1NOS3NOS1NOS2
Dibenzyl Disulfide SCHEMBL5313009 0.70 ALDH1A1 (0.50) TSHRIDO1NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090011963-A1 TRUCK FLEET FUEL ECONOMY BY THE USE OF OPTIMIZED ENGINE OIL, TRANSMISSION FLUID, AND GEAR OIL AFTON CHEMICAL CORPORATION 2009-01-08 US disclosed
US-5703023-A VINYLAROMATIC-MALEIC ESTER POLYMERIC VISCOSITY INDEX IMPROVER ETHYL CORPORATION (US) 1997-12-30 US disclosed
US-5652201-A INCLUDING OIL-SOLUBLE OVERBASED ALKALINE EARTH METAL-CONTAINING SULFONATE DETERGENT, BORON-FREE ADDITIVE FORMED BY HEATING ASHLESS DISPERSANT CONTAINING BASIC NITROGEN AND/OR HYDROXYL GROUP WITH INORGANIC PHOSPHORUS ACID ETHYL PETROLEUM ADDITIVES INC. (US) 1997-07-29 US disclosed
US-5498355-A CRANKCASE OIL DISPERSANT, A FIRST SUCCINYLATED POLYALKYLENE REACTED WITH AN ALKYLENE POLYAMINE AND A SECOND REACTED WITH A HYDROXYPROPYLATED ALKYLENE POLYAMINE ETHYL CORPORATION (US) 1996-03-12 US disclosed
EP-0516461-B1 Lubricating oil compositions and concentrates and the use thereof ETHYL PETROLEUM ADDITIVES INC (US) 1996-02-28 EP disclosed
EP-0516461-A1 Lubricating oil compositions and concentrates and the use thereof ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-12-02 EP disclosed
EP-0493928-A1 Lubricating oil compositions, concentrates and the use thereof ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-07-08 EP disclosed
US-4162985-A HYDROGENATED VINYLARENE-CONJUGATED DIENE POLYMER, EXTREME PRESSURE COMPONENT, OIL BASE THE LUBRIZOL CORPORATION (US) 1979-07-31 US disclosed