SCHEMBL766520

SCHEMBL766520

ClC(SSC(Cl)c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
DPP4 P27487 2/20 0.41
F2 P00734 1/20 0.41
HTR2A P28223 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
CYP2D6 P10635 2/20 0.36
SRC P12931 1/20 0.36
LMNA P02545 2/20 0.35
SLC6A4 P31645 2/20 0.35
SLC6A3 Q01959 2/20 0.35
HRH1 P35367 1/20 0.35
MTOR P42345 1/20 0.35
RAB9A P51151 1/20 0.35
GRM7 Q14831 1/20 0.35
MAPK1 P28482 1/20 0.35
SLC6A2 P23975 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7120944 0.82 TSHR (0.55) TSHRDPP4F2HTR2ATAAR1
SCHEMBL1575568 0.80 TSHR (0.52) TSHRDPP4F2HTR2ATAAR1
SCHEMBL6047976 0.78 TSHR (0.50) TSHRDPP4F2HTR2ATAAR1
SCHEMBL4127900 0.78 TSHR (0.39) TSHRSLC6A4SLC6A3SLC6A2
SCHEMBL11062833 0.76 TSHR (0.48) TSHRDPP4F2CYP2D6SRC
SCHEMBL2155150 0.72 TSHR (0.44) TSHRDPP4F2HTR2ATAAR1
SCHEMBL10679365 0.72 TSHR (0.44) TSHRDPP4F2HTR2ATAAR1
SCHEMBL151375 0.71 TSHR (0.65) TSHRDPP4F2HTR2ATAAR1
SCHEMBL6283476 0.71 TSHR (0.65) TSHRDPP4F2HTR2ATAAR1
SCHEMBL28353 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1610 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122095060-A High-sulfur additives for lubricating oil compositions 2026-05-26 CN disclosed
EP-4581109-B1 GELLING AGENT FOR CALCIUM SULFONATE GREASES LUBRIZOL CORP (US) 2026-05-20 EP disclosed
US-12630779-B2 Transmission lubricants containing molybdenum AFTON CHEMICAL CORPORATION (US) 2026-05-19 US disclosed
US-12630778-B2 Detergent-free and low-ash lubricating composition AFTON CHEMICAL CORPORATION (US) 2026-05-19 US disclosed
US-12624269-B2 Heat transfer fluids comprising isomeric branched paraffin dimers derived from linear alpha olefins and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2026-05-12 US disclosed
EP-3947611-B1 A MIDDLE-PRESSURE POLYMERIZATION PROCESS FOR LIQUID ETHYLENE COPOLYMERS BASF SE (DE) 2026-05-06 EP disclosed
EP-4732220-A1 METHODS AND SYSTEMS ENABLING CIRCULARITY FOR MACHINE FLUIDS BASF SE (DE) 2026-04-29 EP disclosed
EP-4731732-A1 LUBRICANT ADDITIVES FOR PERFORMANCE BOOSTING Afton Chemical Corporation (US) 2026-04-29 EP disclosed
EP-4731730-A1 POLYALKYLENE GLYCOL BASE OIL FOR REDUCING NOX IN GAS FUELED COMBUSTION ENGINES BASF SE (DE) 2026-04-29 EP disclosed
EP-4514929-B1 ADDITIVES WITH HIGH SULFURIZATION FOR LUBRICATING OIL COMPOSITIONS AFTON CHEMICAL CORP (US) 2026-04-08 EP disclosed
US-3962105-A LUBRICATING COMPOSITIONS THE LUBRIZOL CORPORATION (US) 1976-06-08 US disclosed
US-3959159-A Nitrogen-containing mixed esters and lubricants THE LUBRIZOL CORPORATION (US) 1976-05-25 US disclosed
US-3957854-A FUEL ADDITIVES, LUBRICANTS THE LUBRIZOL CORPORATION (US) 1976-05-18 US disclosed
US-3957855-A FUEL ADDITIVES, LUBRICANTS THE LUBRIZOL CORPORATION (US) 1976-05-18 US disclosed
US-3956149-A CARBOXY-CONTAINING COPOLYMER THE LUBRIZOL CORPORATION (US) 1976-05-11 US disclosed
US-3953347-A EXTREME PRESSURE ADDITIVES FOR LUBRICANTS THE LUBRIZOL CORPORATION (US) 1976-04-27 US disclosed
US-3951830-A Basic metal salts of sulfur- and methylene-bridged polyphenol compositions, and epoxide-reacted derivatives thereof, and lubricants containing them THE LUBRIZOL CORPORATION (US) 1976-04-20 US disclosed
US-3948800-A Dispersant compositions THE LUBRIZOL CORPORATION (US) 1976-04-06 US disclosed
US-3933761-A INTERPOLYMERS THE LUBRIZOL CORPORATION (US) 1976-01-20 US disclosed
US-3932290-A Phosphorus-containing friction modifiers for functional fluids THE LUBRIZOL CORPORATION (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624269-B2 Heat transfer fluids comprising isomeric branched paraffin dimers derived from linear alpha olefins and use thereof SCO2, POU2F1, ABCF2 TSHR 3028/4885DPP4 4295/4885F2 35/4885
US-12630779-B2 Transmission lubricants containing molybdenum ZKSCAN2, ZFR, SLC39A11 TSHR 947/4885DPP4 622/4885F2 473/4885
US-12630778-B2 Detergent-free and low-ash lubricating composition SFN, PSPH, C9 TSHR 1060/4885DPP4 2081/4885F2 1852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.