SCHEMBL412804

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10241235	0.94	MAPK1 (0.61)	MAPK1POLBHTTPDGFRBABCB1
	Hydrochloric Acid SCHEMBL412165	0.93	MAPK1 (0.60)	MAPK1POLBHTTPDGFRBABCB1
	SCHEMBL14619537	0.91	MAPK1 (0.45)	MAPK1POLBHTTPDGFRBKDM4E
	SCHEMBL10189704	0.87	MAPK1 (0.43)	MAPK1POLBHTTPDGFRBKDM4E
	SCHEMBL407089	0.86	GAK (0.47)	MAPK1PDGFRBTUBB4ATUBBTUBA3C
	SCHEMBL14619539	0.85	KDM4E (0.56)	MAPK1POLBHTTPDGFRBTUBB4A
	SCHEMBL408099	0.83	TUBB4A (0.47)	MAPK1POLBHTTPDGFRBTUBB4A
	SCHEMBL411388	0.82	TUBB4A (0.54)	MAPK1PDGFRBTUBB4ATUBBTUBA3C
	SCHEMBL10189738	0.81	MAPK1 (0.45)	MAPK1POLBHTTPDGFRBTUBB4A
	SCHEMBL411640	0.81	KDM4E (0.44)	MAPK1TUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.