Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768751 | 0.86 | PRCP (0.49) | PRCPGRM8GRM4ROCK2ROCK1 | |
| SCHEMBL31000654 | 0.86 | PRCP (0.49) | PRCPGRM8GRM4ROCK2ROCK1 | |
| SCHEMBL1768752 | 0.86 | PRCP (0.49) | PRCPGRM8GRM4ROCK2ROCK1 | |
| SCHEMBL31000717 | 0.86 | PRCP (0.49) | PRCPGRM8GRM4ROCK2ROCK1 | |
| SCHEMBL7050992 | 0.74 | CYP1A2 (0.36) | GRM8GRM4AKR1C3AKR1C2NAPRT | |
| SCHEMBL13374285 | 0.73 | LMNA (0.53) | GRM8GRM4ROCK2ROCK1NAPRT | |
| SCHEMBL2452369 | 0.73 | LMNA (0.53) | GRM8GRM4ROCK2ROCK1NAPRT | |
| SCHEMBL2452367 | 0.73 | LMNA (0.53) | GRM8GRM4ROCK2ROCK1NAPRT | |
| SCHEMBL31000749 | 0.73 | LMNA (0.53) | GRM8GRM4ROCK2ROCK1NAPRT | |
| SCHEMBL7052263 | 0.72 | CYP2D6 (0.43) | ROCK2ROCK1AKR1C3AKR1C2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517668-B1 | Process for the production of protein products in aspergillus | NOVOZYMES A/S (DK) | 2009-04-14 | — | — | US | disclosed |
| US-5965384-A | CULTURING ASPERGILLUS ORYZAE TRANSFORMED WITH EXPRESSION VECTOR OF REGULATORY SEQUENCES AND DNA SEQUENCES CODING FOR HUMICOLA LANUGINOSA LIPASE, RECOVERING LIPASE WITH DIFFERENT GLYCOSYLATION AND HEAT AND/OR PROTEOLYTIC RESISTANCE | NOVO NORDISK A/S (DK) | 1999-10-12 | — | — | US | disclosed |
| US-5874558-A | VECTOR SYSTEM; GREATER GLYCOSYLATION, IMPROVED THERMOSTABILITY | NOVO NORDISK (DK) | 1999-02-23 | — | — | US | disclosed |
| US-5863759-A | EXPRESSION OF PROTEIN PRODUCT IN ASPERGILLUS WITH GENETIC ENGINEERING WITH DNA SEQUENCES | NOVO NORDISK A/S (DK) | 1999-01-26 | — | — | US | disclosed |
| US-5766912-A | GENETICALLY ENGINEERED HUMICOLA LIPASE, HAVING GLYCOSYLATION DIFFERENT FROM NATIVE LIPASE, BEING MORE THERMOSTABLE AND/OR MORE RESISTANT TO PROTEOLYSIS | NOVO NORDISK A/S (DK) | 1998-06-16 | — | — | US | disclosed |
| US-5536661-A | Process for the production of protein products in aspergillus | NOVO NORDISK A/S (DK) | 1996-07-16 | — | — | US | disclosed |
| EP-0305216-B1 | Recombinant Humicola lipase and process for the production of recombinant humicola lipases | NOVO NORDISK AS (DK) | 1995-08-02 | — | — | EP | disclosed |
| EP-0345315-B1 | PS2 PROTEIN DERIVATIVE | ADEREGEM (FR) | 1993-03-24 | — | — | EP | disclosed |
| EP-0345315-A1 | PS2 PROTEIN DERIVATIVE | ADEREGEM (FR) | 1989-12-13 | — | — | EP | disclosed |
| WO-1989003845-A1 | PS2 PROTEIN DERIVATIVE | ADEREGEM (FR) | 1989-05-05 | — | — | WO | disclosed |
| EP-0305216-A1 | Recombinant Humicola lipase and process for the production of recombinant humicola lipases | NOVO NORDISK A/S (DK) | 1989-03-01 | — | — | EP | disclosed |