SCHEMBL4129

SCHEMBL4129

OB(O)c1ccccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
LMNA P02545 1/20 0.47
ENPP2 Q13822 4/20 0.46
ALDH1A1 P00352 2/20 0.43
ORAI1 Q96D31 1/20 0.39
ORAI2 Q96SN7 1/20 0.39
ORAI3 Q9BRQ5 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
LIPE Q05469 1/20 0.38
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404220 1.00 TSHR (0.47) TSHRLMNAENPP2ALDH1A1ORAI1
Benzene SCHEMBL28042388 0.97 LMNA (0.45) TSHRLMNAENPP2ALDH1A1ORAI1
SCHEMBL28117905 0.97 TSHR (0.45) TSHRLMNAENPP2ALDH1A1ORAI1
SCHEMBL31125058 0.89 ENPP2 (0.39) TSHRLMNAENPP2ALDH1A1ORAI1
SCHEMBL14217841 0.84 TSHR (0.43) TSHRLMNAENPP2ALDH1A1ORAI1
SCHEMBL20953849 0.83 ENPP2 (0.40) TSHRLMNAENPP2ORAI1ORAI2
SCHEMBL28066888 0.82 SMN1; SMN2 (0.42) LMNAENPP2ALDH1A1MAPT
SCHEMBL22703498 0.80 CYP2A6 (0.44) TSHRLMNAENPP2ALDH1A1
SCHEMBL16104430 0.80 ENPP2 (0.45) TSHRLMNAENPP2ALDH1A1ORAI1
SCHEMBL4991 0.79 TSHR (0.48) TSHRLMNAENPP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5972 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122081295-A Phenylboronic acid-based living material for strengthening biological manufacturing process and application thereof 2026-05-26 CN claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-119978389-A Boron-containing oligomer for aging-resistant high-transparency addition-type silicon rubber, and preparation method and application thereof 中国科学院化学研究所 2025-05-13 CN claimed
CN-118772131-A Biaryl compound and preparation method and application thereof 河南大学 2024-10-15 CN claimed
CN-118758925-A Colorimetric indicator displacement sensing array and application thereof in white tea rapid identification 集美大学 2024-10-11 CN claimed
CN-118370856-A Antibacterial and antioxidant composition and preparation method of diabetic ulcer dressing 青岛大学 2024-07-23 CN claimed
CN-117699779-A Carbon dot solidifying agent and application thereof 厦门大学 2024-03-15 CN claimed
CN-113621215-B Preparation method of organic-inorganic hybrid biomass phenolic resin ablation-resistant material 哈尔滨工业大学 2024-02-09 CN claimed
CN-115160356-B Method for effectively preparing vinyl silane derivative through cascade three-component reaction 南阳师范学院 2024-01-26 CN claimed
CN-101333226-A Chiral dual ring [4.4.0] diborate and method for preparing same UNIV WUHAN (CN) 2008-12-31 CN claimed
US-20080200684-A1 Process for Preparing Ethyl (s)-2-Ethoxy-4-[N-[1-(2-Piperidinophenyl)-3-Methyl-1-Butyl]Aminocarbonyl Methyl]Benzoate and Use Thereof for the Preparation of Repaglinide ACTAVIS GROUP PTC HF (IS) 2008-08-21 US claimed
WO-2008099286-A2 IMPROVED PROCESS FOR PREPARING ETHYL (S)-2-ETHOXY-4-[N-[1-(2- PIPERIDINOPHENYL)-3-METHYL-1-BUTYL]AMINOCARBONYL METHYL]BENZOATE AND USE THEREOF FOR THE PREPARATION OF REPAGLINIDE ACTAVIS GROUP PTC EHF (US) 2008-08-21 WO claimed
CN-101157590-A Method for preparing alpha-aryl carbonyl compound UNIV WUHAN (CN) 2008-04-09 CN claimed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO claimed
WO-2007129810-A1 SYNTHESIS OF VINYLPHENYLPYRIDINE AND LIVING ANIONIC POLYMERIZATION GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2007-11-15 WO claimed
US-7037905-B2 Pharmaceutical use of boronic acids and esters thereof NOVO NORDISK A/S (DK) 2006-05-02 US claimed
US-20040053889-A1 Pharmaceutical use of boronic acids and esters thereof NOVO NORDISK A/S (DK) 2004-03-18 US claimed
WO-2003105860-A1 PHARMACEUTICAL USE OF BORONIC ACIDS AND ESTERS THEREOF NOVO NORDISK A/S (DK) 2003-12-24 WO claimed
WO-1995005081-A1 BIOCIDAL COMPOSITIONS CONTAINING ORGANOBORON COMPOUNDS U.S. BORAX INC. (US) 1995-02-23 WO claimed