Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31154113 | 0.81 | HSD17B10 (0.49) | HSD17B10ALDH1A1POLBCXCR2MAPT | |
| SCHEMBL2573400 | 0.80 | HSD17B10 (0.48) | HSD17B10ALDH1A1POLBCXCR2HSP90AA1 | |
| SCHEMBL646337 | 0.80 | MAPT (0.34) | HSD17B10ALDH1A1POLBMAPTKDM4E | |
| SCHEMBL13903680 | 0.78 | MEN1 (0.46) | HSD17B10ALDH1A1POLBMAPTKDM4E | |
| SCHEMBL10908088 | 0.77 | LMNA (0.41) | HSD17B10ALDH1A1POLBCXCR2HTT | |
| SCHEMBL4149675 | 0.77 | RET (0.46) | ALDH1A1POLBCXCR2MAPTKDM4E | |
| SCHEMBL12292136 | 0.76 | HSD17B10 (0.44) | HSD17B10ALDH1A1POLBCXCR2LMNA | |
| SCHEMBL10167468 | 0.75 | KMT2A (0.45) | HSD17B10ALDH1A1POLBCXCR2MAPT | |
| SCHEMBL12292129 | 0.74 | HSD17B10 (0.43) | HSD17B10ALDH1A1POLBCXCR2MAPT | |
| SCHEMBL13903626 | 0.74 | HSD17B10 (0.43) | HSD17B10ALDH1A1POLBKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069317-A1 | Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives | BASF SE (DE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069317-A1 | Insecticidal Methods Using 3-Amino-1,2-Benzisothiazole Derivatives | AAAS, API5, ATL3 | HSD17B10 3186/4885ALDH1A1 731/4885POLB 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.